Research Laboratory for Vector-Borne Diseases, Queen Astrid Military Hospital, Brussels B-1120, Belgium.
Viruses. 2014 Jan 7;6(1):151-71. doi: 10.3390/v6010151.
The English sweating sickness caused five devastating epidemics between 1485 and 1551, England was hit hardest, but on one occasion also mainland Europe, with mortality rates between 30% and 50%. The Picardy sweat emerged about 150 years after the English sweat disappeared, in 1718, in France. It caused 196 localized outbreaks and apparently in its turn disappeared in 1861. Both diseases have been the subject of numerous attempts to define their origin, but so far all efforts were in vain. Although both diseases occurred in different time frames and were geographically not overlapping, a common denominator could be what we know today as hantavirus infections. This review aims to shed light on the characteristics of both diseases from contemporary as well as current knowledge and suggests hantavirus infection as the most likely cause for the English sweating sickness as well as for the Picardy sweat.
英国汗热病在 1485 年至 1551 年间引发了五次毁灭性的流行,英国受灾最为严重,但有一次也波及到了欧洲大陆,死亡率在 30%至 50%之间。皮卡迪汗热病大约在英国汗热病消失 150 年后,即 1718 年在法国出现。它导致了 196 次局部爆发,并于 1861 年显然消失。这两种疾病都曾多次试图确定其起源,但迄今为止,所有努力都白费了。尽管这两种疾病发生在不同的时间框架内,地理上没有重叠,但一个共同点可能是我们今天所知的汉坦病毒感染。这篇综述旨在从当代和当前的知识出发,阐明这两种疾病的特征,并提出汉坦病毒感染是导致英国汗热病和皮卡迪汗热病的最可能原因。