Chae Ji Yun, Park Gil Young, Kim Jae Heon, Kim Hyung Jee, Bae Jae Hyun, Lee Jeong Gu, Moon Du Geon, Oh Mi Mi
Department of Urology, Korea University Guro Hospital, Korea University College of Medicine, Seoul, Republic of Korea.
Korea University, College of Medicine, Republic of Korea.
Eur J Obstet Gynecol Reprod Biol. 2014 Mar;174:146-9. doi: 10.1016/j.ejogrb.2013.12.015. Epub 2013 Dec 17.
It has been hypothesized that women with significant pelvic organ prolapse (POP), particularly of the anterior vaginal wall, may have voiding dysfunction (VD). Rarely, different compartments of the vagina have been examined closely for VD. This study attempts to further elucidate the correlation between POP and VD by using the standardized Pelvic Organ Prolapse Quantification (POP-Q) staging system.
The clinical records of 66 women who underwent cystocele (≥POP-Q stage III) repair with concomitant midurethral sling were reviewed. Urodynamic study and POP-Q examination were performed preoperatively. The subjects were divided into two groups according to the presence of VD, which was defined as the presence of at least one of the following criteria: maximal flow rate below 15mL/s or postvoid residual urine volume (PVR) above 50mL on preoperative uroflowmetry. Age, parity, uroflowmetry and urodynamic parameters were compared between the two groups.
Of 66 women, 36 had VD preoperatively. In the VD group, failure in the postoperative voiding trial was more frequent (p=0.040), with lower maximal flow rate (p=0.007) and higher PVR (p=0.034). POP-Q stage was significantly higher (p=0.018), and points Aa and Ba were significantly longer (p=0.005 and p=0.006, respectively) in the VD group. POP-Q stage with points Aa and Ba were significantly correlated with the presence of preoperative VD, and moderately correlated with PVR.
The prevalence of VD in patients with cystocele is high (55%). Points Aa and Ba of POP-Q stage had positive correlations with VD in patients with cystocele.
据推测,患有严重盆腔器官脱垂(POP)尤其是阴道前壁脱垂的女性可能存在排尿功能障碍(VD)。很少有研究对阴道不同区域进行密切的排尿功能障碍检查。本研究试图通过使用标准化的盆腔器官脱垂定量(POP-Q)分期系统进一步阐明POP与VD之间的相关性。
回顾了66例行膀胱膨出(≥POP-Q III期)修复术并同期行中段尿道吊带术的女性患者的临床记录。术前进行了尿动力学研究和POP-Q检查。根据是否存在VD将受试者分为两组,VD定义为术前尿流率检查中至少符合以下一项标准:最大尿流率低于15mL/s或排尿后残余尿量(PVR)高于50mL。比较两组患者的年龄、产次、尿流率和尿动力学参数。
66例女性患者中,36例术前存在VD。在VD组中,术后排尿试验失败更为常见(p=0.040),最大尿流率较低(p=0.007),PVR较高(p=0.034)。VD组的POP-Q分期显著更高(p=0.018),Aa点和Ba点显著更长(分别为p=0.005和p=0.006)。POP-Q分期及Aa点和Ba点与术前VD的存在显著相关,与PVR中度相关。
膀胱膨出患者中VD的患病率较高(55%)。膀胱膨出患者中,POP-Q分期的Aa点和Ba点与VD呈正相关。