Sandvoss G, Stoltenburg-Didinger G, Yasargil M G
Neurochirurgia (Stuttg). 1987 May;30(3):65-8. doi: 10.1055/s-2008-1053659.
Operations were carried out on eight cats using a transcervical, transclival approach to expose the sixth cranial nerve just beside the basilar artery. In one case 5 mm of the nerve were resected; three months later no reinnervation was seen. In another cat the nerve ends were merely adapted, and good regeneration was seen despite slight neuroma formation. In a third case TabotampR and Aron-Alpha R were used to repair the skull base; this resulted in a neuroma and in atrophy of the sixth cranial nerve with scar adhesions rendering regeneration impossible. In five cases the transsected nerves were glued together with a fibrin adhesive, with excellent results: very good regeneration and reinnervation occurred within three months with ideal parallel alignment of the nerve fibres at the site of the lesion.
对八只猫进行了手术,采用经颈、经斜坡入路暴露位于基底动脉旁的第六对脑神经。其中一例切除了5毫米的神经;三个月后未见神经再支配。在另一只猫中,仅将神经断端对合,尽管有轻微的神经瘤形成,但仍可见良好的再生。在第三例中,使用TabotampR和Aron-Alpha R修复颅底;这导致了神经瘤和第六对脑神经萎缩,并伴有瘢痕粘连,使再生变得不可能。在五例中,用纤维蛋白粘合剂将横断的神经粘合在一起,结果极佳:三个月内出现了非常好的再生和神经再支配,神经纤维在病变部位理想地平行排列。