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美国住院患者便秘负担:1997 年至 2010 年美国全国趋势分析。

Inpatient burden of constipation in the United States: an analysis of national trends in the United States from 1997 to 2010.

机构信息

Division of Gastroenterology, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts, USA.

Macquarie University, Sydney, New South Wales, Australia.

出版信息

Am J Gastroenterol. 2014 Feb;109(2):250-6. doi: 10.1038/ajg.2013.423. Epub 2014 Jan 14.

Abstract

OBJECTIVES

Constipation is one of the most common outpatient diagnoses in primary care and gastroenterology clinics; however, there is limited data on the inpatient burden of constipation in the United States. The aim of this study was to evaluate inpatient admission rates, length of stay, and associated costs related to constipation from 1997 to 2010.

METHODS

We analyzed the National Inpatient Sample Database for all patients in which constipation (ICD-9 codes: 564.0-564.09) was the principal discharge diagnosis from 1997 to 2010. The statistical significance of the difference in the number of hospital discharges, length of stay, and hospital costs over the study period was determined by utilizing the Spearman's coefficient to describe various trends.

RESULTS

Between 1997 and 2010, the number of hospitalizations for patients with a primary discharge diagnosis of constipation increased from 21,190 patients to 48,450 (P<0.001, GoF test), whereas the mean length of hospital stay increased only slightly from 3.0 days to 3.1 days (b=0.008 (0.003-0.014); P=0.004). The mean charges per hospital discharge for constipation increased from $8869 in 1997 (adjusted for long-term inflation) to $17,518 in 2010 (b=745.4 (685.3-805.6); P<0.001)), whereas the total costs increased from $188,109,249 (adjusted for inflation) in 1997 to $851,713,263 in 2010. Although the elderly (65-84 years) accounted for the largest percentage of constipation discharges, patients in the 1-17 years age group had the highest frequency of constipation per 10,000 discharges.

CONCLUSIONS

The number of inpatient discharges for constipation and associated costs has significantly increased between 1997 and 2010.

摘要

目的

便秘是初级保健和胃肠病学诊所中最常见的门诊诊断之一;然而,美国住院患者便秘负担的数据有限。本研究旨在评估 1997 年至 2010 年期间与便秘相关的住院入院率、住院时间和相关费用。

方法

我们分析了 1997 年至 2010 年期间,国家住院患者样本数据库中所有以便秘(ICD-9 代码:564.0-564.09)为主要出院诊断的患者。利用 Spearman 系数描述各种趋势,确定研究期间住院出院人数、住院时间和住院费用差异的统计学意义。

结果

1997 年至 2010 年间,因主要诊断为便秘而住院的患者人数从 21190 例增加到 48450 例(P<0.001,GoF 检验),而平均住院时间仅略有增加,从 3.0 天增加到 3.1 天(b=0.008(0.003-0.014);P=0.004)。便秘患者每次住院的平均费用从 1997 年的 8869 美元(长期通胀调整后)增加到 2010 年的 17518 美元(b=745.4(685.3-805.6);P<0.001)),而总费用从 1997 年的 188109249 美元(通胀调整后)增加到 2010 年的 851713263 美元。尽管 65-84 岁的老年人占便秘出院人数的最大比例,但 1-17 岁年龄组的便秘发生率最高。

结论

1997 年至 2010 年间,因便秘住院的人数和相关费用显著增加。

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