产后贫血中的静脉铁剂治疗
Intravenous iron in postpartum anemia.
作者信息
Jain Geeta, Palaria Urmila, Jha S K
机构信息
Department of O&G, Govt. Medical College, Haldwani, Rampur Road, Haldwani, Uttarakhand India.
Department of Anaesthesia, Govt. Medical College, Haldwani, Rampur Road, Haldwani, Uttarakhand India.
出版信息
J Obstet Gynaecol India. 2013 Mar;63(1):45-8. doi: 10.1007/s13224-012-0240-y. Epub 2013 Apr 16.
OBJECTIVE
To compare effectiveness of intravenous iron-sucrose versus oral ferrous fumarate in postpartum anemia.
METHODS
In this study, 40 women with postpartum anemia with hemoglobin (Hb) less than 8 g/dl within 48 h postpartum were randomised into two groups. Group I consisted of 20 women who received 300-600 mg of intravenous iron-sucrose every alternate day for 3 days. Group II consisted of 20 women who were given 300 mg ferrous fumarate orally daily for 14 days.
RESULTS
On day 14, the increase in mean Hb level in group I was 2.4 g/dl in comparison to 1.2 g/dl in group II. Women in group I had significantly higher mean Hb values on days 7 and 14 (p < 0.001) than women in group II.
CONCLUSION
These results suggest that intravenous iron-sucrose increases the Hb level more rapidly than oral ferrous fumarate in postpartum anemia without any serious side effects.
目的
比较静脉注射蔗糖铁与口服富马酸亚铁治疗产后贫血的效果。
方法
本研究将40例产后48小时内血红蛋白（Hb）低于8 g/dl的产后贫血妇女随机分为两组。第一组由20名妇女组成，她们每隔一天接受300 - 600毫克静脉注射蔗糖铁，共3天。第二组由20名妇女组成，她们每天口服300毫克富马酸亚铁，共14天。
结果
在第14天，第一组平均Hb水平升高了2.4 g/dl，而第二组为1.2 g/dl。第一组妇女在第7天和第14天的平均Hb值显著高于第二组妇女（p < 0.001）。
结论
这些结果表明，在产后贫血中，静脉注射蔗糖铁比口服富马酸亚铁能更迅速地提高Hb水平，且无任何严重副作用。
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