Arushanian É B
Eksp Klin Farmakol. 2013;76(9):32-7.
Melatonin, which is produced by pineal gland and peripheral tissue cells, has a very wide spectrum of pharmacological activity. Available experimental data show that melatonin can provide universal protection of central nervous system and internal organs from damages. These properties can be successfully used in therapy of many diseases. However, for some reasons, the pharmacological activity of melatonin is not properly founded in clinical practice. Conditions for the discovery of therapeutic possibilities of melatonin are discussed, including prospects for its complex use in combination with traditional drugs.
褪黑素由松果体和外周组织细胞产生,具有非常广泛的药理活性。现有实验数据表明,褪黑素能对中枢神经系统和内脏器官提供全面保护,使其免受损伤。这些特性可成功应用于多种疾病的治疗。然而,由于某些原因,褪黑素的药理活性在临床实践中并未得到充分应用。本文讨论了发现褪黑素治疗潜力的条件,包括其与传统药物联合使用的前景。