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三胎妊娠无症状宫颈短缩患者行环扎术的应用。

Use of cerclage in triplet pregnancies with an asymptomatic short cervix.

机构信息

Department of Obstetrics and Gynecology, University of California, Irvine, 101 The City Dr S, Building 56, Suite 800, Orange, CA 92869 USA.

出版信息

J Ultrasound Med. 2014 Feb;33(2):343-7. doi: 10.7863/ultra.33.2.343.

Abstract

OBJECTIVES

The purpose of this study was to compare the outcomes of triplet pregnancies in women with asymptomatic cervical shortening with and without a cervical cerclage.

METHODS

A retrospective review of all triplet pregnancies with biweekly serial cervical length surveillance was performed. Cervical shortening was defined as a cervical length of 2.5 cm or less before 24 weeks' gestation. Patients with cervical shortening managed with cerclage were compared to those managed expectantly. The primary outcome was the gestational age at delivery, with secondary outcomes including birth weight, neonatal intensive care unit length of stay, and composite neonatal outcome. Statistical significance was defined as P < .05.

RESULTS

Sixteen patients underwent cerclage placement versus 8 managed expectantly (control group). The median gestational ages at delivery were similar between the groups (cerclage, 31.3 weeks; interquartile range [IQR], 29.3-32.3 weeks; control, 29.8 weeks; IQR, 27.5-32.4 weeks; P = .71). The median birth weights were also similar between the groups (cerclage, 1283 g; IQR, 800-1626 g; control, 1109 g; IQR, 776-1500 g; P = .54). There was no significant difference in composite neonatal outcomes between the cerclage and control groups (P = .67).

CONCLUSIONS

In this limited case-control study, we found no benefit in terms of pregnancy prolongation or neonatal outcomes with cerclage placement for triplet gestations complicated by an asymptomatic short cervix.

摘要

目的

本研究旨在比较无症状宫颈缩短的三胞胎孕妇行宫颈环扎术与期待治疗的结局。

方法

对所有行双周宫颈长度监测的三胞胎妊娠进行回顾性分析。宫颈缩短定义为妊娠 24 周前宫颈长度≤2.5cm。将行宫颈环扎术治疗的宫颈缩短患者与期待治疗的患者进行比较。主要结局为分娩时的孕周,次要结局包括出生体重、新生儿重症监护病房住院时间和复合新生儿结局。统计学显著性定义为 P<.05。

结果

16 例患者行宫颈环扎术,8 例患者行期待治疗(对照组)。两组分娩时的中位孕周相似(环扎组,31.3 周;四分位距[IQR],29.3-32.3 周;对照组,29.8 周;IQR,27.5-32.4 周;P=.71)。两组的中位出生体重也相似(环扎组,1283g;IQR,800-1626g;对照组,1109g;IQR,776-1500g;P=.54)。环扎组和对照组的复合新生儿结局无显著差异(P=.67)。

结论

在这项有限的病例对照研究中,我们发现无症状宫颈短的三胞胎妊娠行宫颈环扎术并不能延长妊娠或改善新生儿结局。

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