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Degradation of platelet-von Willebrand factor complexes by plasmin: an alternative/backup mechanism to ADAMTS13.

作者信息

Chauhan Anil K

机构信息

Department of Internal Medicine, University of Iowa, Iowa City, IA.

出版信息

Circulation. 2014 Mar 25;129(12):1273-5. doi: 10.1161/CIRCULATIONAHA.114.008298. Epub 2014 Jan 21.

Abstract
摘要

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本文引用的文献

1
Plasmin cleavage of von Willebrand factor as an emergency bypass for ADAMTS13 deficiency in thrombotic microangiopathy.
Circulation. 2014 Mar 25;129(12):1320-31. doi: 10.1161/CIRCULATIONAHA.113.006727. Epub 2014 Jan 21.
2
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Hematology Am Soc Hematol Educ Program. 2013;2013:292-9. doi: 10.1182/asheducation-2013.1.292.
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Treatment of thrombotic microangiopathy with a focus on new treatment options.
Hamostaseologie. 2013 May 29;33(2):149-59. doi: 10.5482/HAMO-13-01-0004.
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A new mouse model mimicking thrombotic thrombocytopenic purpura: correction of symptoms by recombinant human ADAMTS13.
Blood. 2012 Jun 21;119(25):6128-35. doi: 10.1182/blood-2011-09-380535. Epub 2012 Apr 23.
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Modulation of the von Willebrand factor-dependent platelet adhesion through alternative proteolytic pathways.
Thromb Res. 2012 Apr;129(4):e41-6. doi: 10.1016/j.thromres.2011.11.021. Epub 2011 Dec 15.
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N-acetylcysteine reduces the size and activity of von Willebrand factor in human plasma and mice.
J Clin Invest. 2011 Feb;121(2):593-603. doi: 10.1172/JCI41062. Epub 2011 Jan 25.
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Leukocyte proteases cleave von Willebrand factor at or near the ADAMTS13 cleavage site.
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