Department of Malignant Hematology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL.
Department of Hematopathology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL.
Mediterr J Hematol Infect Dis. 2014 Jan 1;6(1):e2014001. doi: 10.4084/MJHID.2014.001.
Kikuchi-Fujimoto Disease (KFD), also known as histiocytic necrotizing lymphadenitis [corrected], is a benign, self-limiting disease that manifests primarily as cervical lymphadenopathy but may include low-grade fever, headache, and fatigue. There is a higher incidence of KFD in women aged 20-35 years and in Asian populations. A PubMed search revealed 590 articles that described KFD. Of these, 22 cases have been fully described in the United States. Ten of the 22 (45%) patients were male and 12 (55%) were female, with 20% Caucasian, 20% Asian American, and the remaining 60% of other ethnic backgrounds. In this study, we describe an additional 3 cases of KFD and discuss the diagnosis, pathology, and management of KFD.
菊池古氏病（KFD），也称为组织细胞性坏死性淋巴结炎[已更正]，是一种良性、自限性疾病，主要表现为颈淋巴结病，但可能包括低热、头痛和疲劳。20-35 岁的女性和亚洲人群中 KFD 的发病率较高。在 PubMed 上搜索到 590 篇描述 KFD 的文章。其中，22 例在美国有详细描述。22 例患者中，10 例为男性，12 例为女性，20%为白种人，20%为亚裔美国人，其余 60%为其他种族背景。在本研究中，我们描述了另外 3 例 KFD 病例，并讨论了 KFD 的诊断、病理和治疗。
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