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接受普通外科和血管外科手术的糖尿病患者与非糖尿病患者的手术结果。

Outcomes of diabetic and nondiabetic patients undergoing general and vascular surgery.

作者信息

Serio Stephen, Clements John M, Grauf Dawn, Merchant Aziz M

机构信息

Department of Surgery, Covenant Healthcare, Central Michigan University College of Medicine, Saginaw, MI 48603, USA.

Department of Research, Covenant Healthcare, Central Michigan University College of Medicine, Saginaw, MI 48603, USA.

出版信息

ISRN Surg. 2013 Dec 26;2013:963930. doi: 10.1155/2013/963930.

Abstract

Aims. Preoperative diabetic and glycemic screening may or may not be cost effective. Although hyperglycemia is known to compromise surgical outcomes, the effect of a diabetic diagnosis on outcomes is poorly known. We examine the effect of diabetes on outcomes for general and vascular surgery patients. Methods. Data were collected from the Michigan Surgical Quality Collaborative for general or vascular surgery patients who had diabetes. Primary and secondary outcomes were 30-day mortality and 30-day overall morbidity, respectively. Binary logistic regression analysis was used to identify risk factors. Results. We identified 177,430 (89.9%) general surgery and 34,006 (16.1%) vascular surgery patients. Insulin and noninsulin diabetics accounted for 7.1% and 9.8%, respectively. Insulin and noninsulin dependent diabetics were not at increased risk for mortality. Diabetics are at a slight increased odds than non-diabetics for overall morbidity, and insulin dependent diabetics more so than non-insulin dependent. Ventilator dependence, 10% weight loss, emergent case, and ASA class were most predictive. Conclusions. Diabetics were not at increased risk for postoperative mortality. Insulin-dependent diabetics undergoing general or vascular surgery were at increased risk of overall 30-day morbidity. These data provide insight towards mitigating poor surgical outcomes in diabetic patients and the cost effectiveness of preoperative diabetic screening.

摘要

目的。术前糖尿病和血糖筛查可能具有成本效益,也可能不具有成本效益。虽然已知高血糖会影响手术结果,但糖尿病诊断对手术结果的影响却鲜为人知。我们研究了糖尿病对普通外科和血管外科患者手术结果的影响。方法。从密歇根外科质量协作组织收集了患有糖尿病的普通外科或血管外科患者的数据。主要和次要结局分别为30天死亡率和30天总体发病率。采用二元逻辑回归分析来确定危险因素。结果。我们确定了177430名(89.9%)普通外科患者和34006名(16.1%)血管外科患者。胰岛素依赖型糖尿病患者和非胰岛素依赖型糖尿病患者分别占7.1%和9.8%。胰岛素依赖型糖尿病患者和非胰岛素依赖型糖尿病患者的死亡风险并未增加。糖尿病患者总体发病率的几率略高于非糖尿病患者,胰岛素依赖型糖尿病患者比非胰岛素依赖型糖尿病患者更高。呼吸机依赖、体重减轻10%、急诊病例和美国麻醉医师协会分级是最具预测性的因素。结论。糖尿病患者术后死亡风险并未增加。接受普通外科或血管外科手术的胰岛素依赖型糖尿病患者30天总体发病率风险增加。这些数据为减轻糖尿病患者手术不良结果以及术前糖尿病筛查的成本效益提供了见解。

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