Chinniah Niranthari, Cains Geoffrey David
Department of Dermatology, Liverpool Hospital, Liverpool, Australia.
Australas J Dermatol. 2014 May;55(2):128-31. doi: 10.1111/ajd.12136. Epub 2014 Jan 23.
Hidradenitis suppurativa is a debilitating disorder that can be difficult to manage with current conventional treatment strategies. Given its association with proinflammatory cytokines there has been interest in the use of novel biological monoclonal antibodies. We describe our experience with the use of these agents in six patients in whom conventional treatment had failed, with promising response noted in some patients. A growing number of studies now highlight the efficacy of these agents.
化脓性汗腺炎是一种使人衰弱的疾病,目前的传统治疗策略可能难以对其进行管理。鉴于其与促炎细胞因子有关联,人们对使用新型生物单克隆抗体产生了兴趣。我们描述了在6例传统治疗失败的患者中使用这些药物的经验,部分患者有良好反应。现在越来越多的研究强调了这些药物的疗效。