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Src inhibition is still a relevant target in pancreatic cancer.

作者信息

George Thomas J, Trevino Jose G, Liu Chen

机构信息

Departments of Medicine.

出版信息

Oncologist. 2014 Feb;19(2):211. doi: 10.1634/theoncologist.2013-0410. Epub 2014 Jan 23.

Abstract
摘要

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本文引用的文献

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Phase II study of dasatinib (BMS-354825) in patients with metastatic adenocarcinoma of the pancreas.
Oncologist. 2013;18(10):1091-2. doi: 10.1634/theoncologist.2013-0255. Epub 2013 Sep 26.
2
Biomedicine. Rare cancer successes spawn 'exceptional' research efforts.
Science. 2013 Apr 19;340(6130):263. doi: 10.1126/science.340.6130.263.
4
Targeted inhibition of SRC kinase signaling attenuates pancreatic tumorigenesis.
Mol Cancer Ther. 2010 Aug;9(8):2322-32. doi: 10.1158/1535-7163.MCT-09-1212. Epub 2010 Aug 3.
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Inhibition of SRC tyrosine kinase as treatment for human pancreatic cancer growing orthotopically in nude mice.
Clin Cancer Res. 2004 Dec 1;10(23):8028-36. doi: 10.1158/1078-0432.CCR-04-0621.

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