Hu Donghua, Tang Jieke, Xu Tianxing, Zhong Zhao, Liang Zhaojia, Liang Jianming, Nie Cai, Liu Jiayi, Zou Qirong, Peng Xuemei, Li Yalan
Department of Anesthesia, First Affiliated Hospital of Jinan University; Guangzhou 510630, China. E-mail:
Nan Fang Yi Ke Da Xue Xue Bao. 2014 Jan;34(1):121-3.
To investigate the correlation between arterial partial pressure of CO2 (PaCO2) and end expiratory tidal partial pressure of CO2 (Pet-CO2) in morbidly obese patients during anesthesia for laparoscopic gastric bypass surgery.
Forty morbidly obese patients with a body mass index (BMI) between 35 and 50 kg/m(2) underwent laparoscopic gastric bypass surgery under general anesthesia. PaCO2 and Pet-CO2 were measured after intubation and before induction of pneumoperitoneum (T0), at 30 min (T1), 60 min (T2), and 120 min (T3) during pneumoperitoneum, and at 30 min (T4) and 60 min (T5) after deflation.
At each time point of measurement, Pet-CO2 was lower than PaCO2 in all the patients. PaCO2 and Pet-CO2 were positively correlated before, during, and after pneumoperitoneum (P<0.05). At a moderate pressure of CO2 pneumoperitoneum (16 mmHg), the level of correlation between PaCO2 and Pet-CO2 at T1, T2, and T3 differed from that before and after post-pneumoperitoneum.
PaCO2 and Pet-CO2 are closely correlated during a moderate CO2 pneumoperitoneum in morbidly obese patients undergoing laparoscopic gastric bypass surgery.
探讨病态肥胖患者在腹腔镜胃旁路手术麻醉期间动脉血二氧化碳分压(PaCO2)与呼气末潮气末二氧化碳分压(Pet-CO2)之间的相关性。
40例体重指数(BMI)在35至50kg/m²之间的病态肥胖患者在全身麻醉下接受腹腔镜胃旁路手术。在气管插管后、气腹诱导前(T0)、气腹期间30分钟(T1)、60分钟(T2)和120分钟(T3)以及放气后30分钟(T4)和60分钟(T5)测量PaCO2和Pet-CO2。
在每个测量时间点,所有患者的Pet-CO2均低于PaCO2。气腹前、气腹期间和气腹后PaCO2与Pet-CO2呈正相关(P<0.05)。在中等压力的二氧化碳气腹(16mmHg)下,T1、T2和T3时PaCO2与Pet-CO2的相关性水平与气腹前后不同。
在接受腹腔镜胃旁路手术的病态肥胖患者中等二氧化碳气腹期间,PaCO2与Pet-CO2密切相关。