Academy of Fundamental and Interdisciplinary Sciences, Harbin Institute of Technology, Harbin 150001, China.
Academy of Fundamental and Interdisciplinary Sciences, Harbin Institute of Technology, Harbin 150001, China.
Talanta. 2014 Mar;120:255-61. doi: 10.1016/j.talanta.2013.12.001. Epub 2013 Dec 17.
Improving the site accessibility of molecularly imprinted polymer (MIP) is one of the biggest challenges for application of MIP in solid-phase extraction (SPE). Hierarchically imprinted mesoporous silica polymer was prepared with semicovalently bond imprinting methods based on MCM-41 and SBA-15 mesostructures, aiming to improve the site accessibility of MIP and increase the efficiency of molecularly imprinted-SPE. Characterization and performance tests of the obtained products revealed that molecularly imprinted SBA-15 (MIP-SBA-15) not only retained the mesoporous structure of SBA-15, but also displayed excellent selectivity of MIP to the target molecule. As the MIP-SBA-15 were adopted as the adsorbents of solid-phase extraction for detecting bisphenol A in spiked water samples, the recoveries of spiked samples more than 87%, which reveals that the molecularly imprinted SBA-15 were efficient SPE adsorbents for bisphenol A.
提高分子印迹聚合物（MIP）的键合点位可及性是将 MIP 应用于固相萃取（SPE）的最大挑战之一。本研究采用半共价键合印迹方法，以 MCM-41 和 SBA-15 介孔结构为模板，制备了具有分级印迹结构的介孔硅聚合物，旨在提高 MIP 的键合点位可及性，增加分子印迹固相萃取的效率。对所得产物的表征和性能测试表明，分子印迹 SBA-15（MIP-SBA-15）不仅保留了 SBA-15 的介孔结构，而且对目标分子表现出优异的 MIP 选择性。当 MIP-SBA-15 被用作固相萃取吸附剂检测加标水样中的双酚 A 时，加标样品的回收率均在 87%以上，这表明分子印迹 SBA-15 是双酚 A 的高效 SPE 吸附剂。
