Johkoh Takeshi
Department of Radiology, Kinki Central Hospital of Mutual Aid Association of Public School Teachers, Itami, Japan.
Semin Ultrasound CT MR. 2014 Feb;35(1):24-8. doi: 10.1053/j.sult.2013.10.004. Epub 2013 Oct 17.
Nonspecific interstitial pneumonia (NSIP) is a form of idiopathic interstitial pneumonia characterized histologically by varying degrees of interstitial inflammation and fibrosis that are temporally and morphologically homogeneous in comparison with usual interstitial pneumonia (UIP). Differentiation from UIP is very important because treatment and prognosis are different between NSIP and UIP. Although there are limitations for the differentiation between NSIP and UIP on computed tomography, some computed tomography findings contribute to it. Relatively peribronchovascular distribution, wide extent of areas with ground-glass attenuation, and subpleural sparing are more highly seen in patients with NSIP, whereas wide extent of honeycombing and subpleural distribution are more common characteristics in patients with UIP.
非特异性间质性肺炎（NSIP）是特发性间质性肺炎的一种形式，其组织学特征为不同程度的间质性炎症和纤维化，与寻常型间质性肺炎（UIP）相比，在时间和形态上具有同质性。NSIP与UIP的鉴别非常重要，因为两者的治疗方法和预后不同。虽然在计算机断层扫描（CT）上鉴别NSIP和UIP存在局限性，但一些CT表现有助于鉴别。相对支气管血管周围分布、磨玻璃影广泛分布以及胸膜下 sparing 在NSIP患者中更为常见，而广泛的蜂窝状改变和胸膜下分布在UIP患者中更为常见。
