Straub M, Muselier A, Bron A, Creuzot-Garcher C
Service d'ophtalmologie, centre hospitalier universitaire de Dijon, 3, rue du Faubourg-Raines, 21033 Dijon cedex, France.
Service d'ophtalmologie, centre hospitalier universitaire de Dijon, 3, rue du Faubourg-Raines, 21033 Dijon cedex, France.
J Fr Ophtalmol. 2014 Feb;37(2):125-9. doi: 10.1016/j.jfo.2013.05.012. Epub 2014 Jan 31.
We report the case of a 53-year-old patient referred by his ophthalmologist for a red, painful eye. On exam, he demonstrated findings of granulomatous uveitis with ocular hypertension (38 mm Hg) and a whitish, vascularized iris tumor with invasion of the irido-corneal angle. As our first hypothesis was an iris metastasis, a systemic work-up was carried out, which revealed moderately differentiated broncho-pulmonary carcinoma with multiple metastases (brain, cerebellum and adrenal). Emergency radio-chemotherapy was initiated, and the outcome was good, with rapid regression of the iris metastasis and good efficacy against the primary cancer. After one year of follow-up, the patient developed a metastasis at a new site, and his general condition deteriorated.
我们报告了一名53岁患者的病例,该患者由眼科医生转诊,因眼睛发红、疼痛前来就诊。检查时,他表现出肉芽肿性葡萄膜炎的症状,伴有高眼压(38毫米汞柱),以及一个白色、血管化的虹膜肿瘤,侵犯了虹膜角膜角。由于我们最初的假设是虹膜转移瘤,因此进行了全面的全身检查,结果发现是中度分化的支气管肺癌并伴有多处转移(脑、小脑和肾上腺)。随即启动了紧急放化疗,效果良好,虹膜转移瘤迅速消退,对原发性癌症也有很好的疗效。经过一年的随访,患者在新的部位出现了转移,其总体状况恶化。