Department of Radiology, Loyola University, Stritch School of Medicine, 2160 S. First Ave, Maywood, IL 60153, CA, USA.
Expert Rev Neurother. 2014 Mar;14(3):277-86. doi: 10.1586/14737175.2014.884929. Epub 2014 Feb 4.
The medical management of patients requiring imaging of the head is often complex. This is confounded by growth and development of neuroimaging technology. Summarizing established guidelines and provided answers to commonly asked questions about neurovascular imaging may aid in providing efficient medical care. Noncontrast head computed tomography (CT) is usually the first line in imaging because of its speed and wide-spread availability. More advanced techniques are reserved for more specific questions or when the CT head is non-diagnostic. MRI is the modality of choice for indications that include chronic headache, pulsatile tinnitus, and cerebrovascular diseases including stroke in the subacute or chronic setting. The imaging of stroke is evolving and many advanced techniques including CT and magnetic resonance perfusion are playing an increasing role in diagnosis. Digital subtraction angiography is widely accepted as the gold standard for evaluation of vascular pathology including aneurysm, vascular malformations, Moyamoya syndrome, carotid stenosis and dissection; and offers treatment options. Alternatives such as MR angiography, MR venography, and CT angiography offer similar sensitivity and specificity to conventional digital subtraction angiography. Safety considerations are an important concern. When using iodinated and gadolinium contrast agents, there are potential complications including allergic reactions, lactic acidosis, and nephrogenic systemic fibrosis. Impaired renal function requires modification in the use of contrast during neuroimaging. Neuroimaging during pregnancy is also discussed.
需要进行头部影像学检查的患者的医学管理通常很复杂。神经影像学技术的发展和成长使情况更加复杂。总结既定的指南并提供有关神经血管成像常见问题的答案,可能有助于提供高效的医疗服务。非对比头部计算机断层扫描(CT)通常是成像的首选方法,因为其速度快且广泛可用。更先进的技术仅用于更具体的问题或 CT 头部检查结果不可诊断时。对于包括慢性头痛、搏动性耳鸣以及亚急性或慢性中风等脑血管疾病等适应症,磁共振成像(MRI)是首选的成像方式。中风的影像学正在不断发展,许多先进的技术,包括 CT 和磁共振灌注,在诊断中发挥着越来越重要的作用。数字减影血管造影(DSA)被广泛认为是评估血管病变(包括动脉瘤、血管畸形、烟雾病、颈动脉狭窄和夹层)的金标准;并提供治疗选择。替代方法,如磁共振血管造影(MRA)、磁共振静脉造影(MRV)和 CT 血管造影(CTA),与传统的数字减影血管造影具有相似的敏感性和特异性。安全性考虑是一个重要的关注点。在使用碘造影剂和钆造影剂时,可能会出现包括过敏反应、乳酸性酸中毒和肾源性系统性纤维化在内的潜在并发症。肾功能受损时,需要修改神经影像学检查中使用的造影剂。还讨论了妊娠期间的神经影像学检查。