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多三维计算机断层扫描与多平面重建图像及经口胆管镜检查结果融合在肝门部胆管癌中的应用价值

Usefulness of multi-3-dimensional computed tomograms fused with multiplanar reconstruction images and peroral cholangioscopy findings in hilar cholangiocarcinoma.

作者信息

Nagakawa Yuichi, Kasuya Kazuhiko, Bunso Kyo, Hosokawa Yuichi, Kuwabara Hiroshi, Nakagima Tetsushi, Osakabe Hiroaki, Tsuchiya Takayoshi, Itoi Takao, Tsuchida Akihiko

机构信息

Department of Surgery, Tokyo Medical University, 6-7-1 Nishishinjuku, Shinjuku-ku, Tokyo, 160-0023, Japan.

出版信息

J Hepatobiliary Pancreat Sci. 2014 Apr;21(4):256-62. doi: 10.1002/jhbp.85. Epub 2014 Feb 12.

DOI:10.1002/jhbp.85
PMID:24520072
Abstract

Multiplanar reconstruction (MPR) images are used for assessing horizontal and vertical extent of hilar cholangiocarcinoma, while peroral cholangioscopy (POCS) is used for diagnosing ductal spread and mapping biopsy. We fused conventional 3-dimensional computed tomography (3DCT) with MPR images and POCS findings for preoperative assessment of cholangiocarcinoma. The extent of cancer was assessed using MPR images, which were plotted and fused onto 3DCT cholangiography. In addition, the results of mapping biopsy performed under POCS were marked on virtual endoscopic imaging and transferred onto a 3DCT image. Once an angiographic CT image was fused, a multi-3DCT image was created. The incision line was determined based on these images. Multi-3DCT images were created for 13 patients with hilar cholangiocarcinoma. Of 10 patients who underwent POCS, superficial spread was observed in two. Resection was performed in 12 patients. In two cases, the cut end of the intrahepatic bile duct was positive, resulting in 83.3% diagnostic accuracy for horizontal spread. In all patients, the estimated number of bile ducts was the same as the number of the actual resections. R0 resection was achieved in 10 patients (83.3%). Multi-3DCT imaging proved useful in diagnosing longitudinal ductal spread of hilar cholangiocarcinoma.

摘要

多平面重建(MPR)图像用于评估肝门部胆管癌的水平和垂直范围,而经口胆管镜检查(POCS)用于诊断胆管内扩散并进行活检定位。我们将传统的三维计算机断层扫描(3DCT)与MPR图像及POCS检查结果融合,用于肝门部胆管癌的术前评估。利用MPR图像评估肿瘤范围,并将其绘制并融合到3DCT胆管造影上。此外,在POCS下进行的活检定位结果标记在虚拟内镜成像上,并转移到3DCT图像上。一旦融合了血管造影CT图像,就创建了多3DCT图像。根据这些图像确定切口线。为13例肝门部胆管癌患者创建了多3DCT图像。在接受POCS检查的10例患者中,有2例观察到浅表扩散。12例患者进行了手术切除。2例患者肝内胆管切端阳性,水平扩散的诊断准确率为83.3%。所有患者中,估计的胆管数量与实际切除的数量相同。10例患者(83.3%)实现了R0切除。多3DCT成像在诊断肝门部胆管癌的纵向胆管扩散方面被证明是有用的。

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