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无瘢痕伤口愈合

Scarless wound healing.

作者信息

Bellayr Ian H, Walters Thomas J, Li Yong

机构信息

Children's Hospital of the University of Pittsburgh Medical Center, Pittsburgh, PA, USA ; University of Pittsburgh, Pittsburgh, PA, USA.

United States Army Institute of Surgical Research, Fort Sam Houston, TX, USA.

出版信息

J Am Col Certif Wound Spec. 2010 Jan 11;2(2):40-3. doi: 10.1016/j.jcws.2010.05.001. eCollection 2010 Jun.

DOI:10.1016/j.jcws.2010.05.001
PMID:24527144
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3601888/
Abstract

Scarring results from injuries and disease in mammalian adults and can cause pain and loss of function in the afflicted tissues. This negative aspect of wound repair is not always true for certain amphibians and during fetal development of mammals. Based on this knowledge, scientists and clinicians are investigating the mechanisms and growth factors that contribute to or deter a suitable environment for wound healing. This review summarizes these aspects and challenges for scarless repair.

摘要

在成年哺乳动物中，疤痕是由损伤和疾病导致的，会使患病组织产生疼痛并丧失功能。伤口修复的这一负面影响在某些两栖动物以及哺乳动物的胎儿发育过程中并非总是如此。基于这一认识，科学家和临床医生正在研究有助于或阻碍伤口愈合适宜环境形成的机制和生长因子。本综述总结了无疤痕修复的这些方面及挑战。

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Am J Physiol Lung Cell Mol Physiol. 2010 Jun;298(6):L715-31. doi: 10.1152/ajplung.00361.2009. Epub 2010 Apr 2.
2
Biochemical insights into the role of matrix metalloproteinases in regeneration: challenges and recent developments.
Future Med Chem. 2009 Sep;1(6):1095-1111. doi: 10.4155/fmc.09.83.
3
Role of matrix metalloproteinases in recurrent corneal melting.
Exp Eye Res. 2010 May;90(5):583-90. doi: 10.1016/j.exer.2010.02.002. Epub 2010 Feb 11.
4
Trefoil factor 3 is induced during degenerative and inflammatory joint disease, activates matrix metalloproteinases, and enhances apoptosis of articular cartilage chondrocytes.
Arthritis Rheum. 2010 Mar;62(3):815-25. doi: 10.1002/art.27295.
5
Nanofibrous composites for tissue engineering applications.
Wiley Interdiscip Rev Nanomed Nanobiotechnol. 2009 Jul-Aug;1(4):369-90. doi: 10.1002/wnan.39.
6
Novel selective MMP-13 inhibitors reduce collagen degradation in bovine articular and human osteoarthritis cartilage explants.
Inflamm Res. 2010 May;59(5):379-89. doi: 10.1007/s00011-009-0112-9. Epub 2009 Nov 10.
7
Antifibrosis: to reverse the irreversible.
Clin Rev Allergy Immunol. 2010 Apr;38(2-3):276-86. doi: 10.1007/s12016-009-8157-7.
8
Biomaterial technology for tissue engineering applications.
J R Soc Interface. 2009 Jun 6;6 Suppl 3(Suppl 3):S311-24. doi: 10.1098/rsif.2008.0448.focus. Epub 2009 Mar 4.
9
Matrix metalloproteinase-1 promotes muscle cell migration and differentiation.
Am J Pathol. 2009 Feb;174(2):541-9. doi: 10.2353/ajpath.2009.080509. Epub 2009 Jan 15.
10
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Curr Opin Rheumatol. 2008 Nov;20(6):720-8. doi: 10.1097/BOR.0b013e32830e48e8.

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