Acmaz Gokhan, Aksoy Huseyin, Albayrak Evrim, Baser Muruvet, Ozyurt Sezin, Aksoy Ulku, Unal Dilek
Department of Obstetrics and Gynecology, Kayseri Education and Research Hospital of Medicine, Kayseri, Turkey E-mail :
Asian Pac J Cancer Prev. 2014;15(1):195-8. doi: 10.7314/apjcp.2014.15.1.195.
To evaluate precancerous lesions such as hyperplasia and endometrial polyps in obese postmenopausal women.
Women who were referred with abnormal uterine bleeding in postmenopausal period or the presence of endometrial cells on cervical cytology in our department were investigated. Anthropometric measurements such as height, weight, body mass index, waist/hip ratio and endometrial thickness were compared between a precancerous lesion (hyperplasia and endometrial polyp) group and a pathologically normal group.
We detected statistically significant thickening of endometrium in patients with precancerous lesions. Moreover patients with precancerous lesions had higher body mass index than the pathologically normal group.
We found elevated precancerous lesion rates in overweight and obese women in the postmenopausal period, of interest given that the prevalence of obesity is increasing in most parts of the world. Although screening for endometrial cancer is not recommended for the general population, in high-risk populations like obese postmenopausal women, it may be very important.
评估肥胖绝经后女性的癌前病变，如增生和子宫内膜息肉。
对我科因绝经后子宫异常出血或宫颈细胞学检查发现子宫内膜细胞而转诊的女性进行调查。比较癌前病变（增生和子宫内膜息肉）组与病理正常组之间的人体测量指标，如身高、体重、体重指数、腰臀比和子宫内膜厚度。
我们检测到癌前病变患者的子宫内膜有统计学意义的增厚。此外，癌前病变患者的体重指数高于病理正常组。
我们发现绝经后超重和肥胖女性的癌前病变率升高，鉴于世界上大多数地区肥胖患病率正在上升，这一点值得关注。虽然不建议对普通人群进行子宫内膜癌筛查，但对于肥胖绝经后女性等高危人群，筛查可能非常重要。
