Petersen W, Herbort M, Höynck E, Zantop T, Mayr H
Klinik für Orthopädie und Unfallchirurgie, Martin Luther Krankenhaus, Caspar-Theyß-Str. 27-31, 14193, Berlin, Deutschland,
Oper Orthop Traumatol. 2014 Feb;26(1):63-74. doi: 10.1007/s00064-013-0262-3. Epub 2014 Feb 9.
Debridement and irrigation of the knee joint and the donor site to reduce the amount of bacteria and to remove bacterial enzymes and inflammatory cytokines in cases with infection after replacement of the anterior cruciate ligament (ACL).
Proven infection, suspected infection.
High anesthesiological risk.
The therapy of infections after ACL reconstruction depends on the different stages as described by Gächter. In stage I and II, arthroscopic debridement and irrigation (about 10 l) of all compartments is performed. Several biopsies for microbiological analysis are obtained during surgery. Broad-spectrum antibiotic therapy started immediately after surgery. Once the resistance of the bacteria is known, antibiotic therapy may be changed according to the results. When pain, swelling, elevated CRP, or white blood cells persists, arthroscopic irrigation is repeated. In stage III, a complete arthroscopic synovectomy is performed. When the graft is intact, it is left in situ. Resection is performed in case of graft insufficiency, tunnel malplacement, or persistent infection. When the bone tunnels are affected, they should be debrided. In stage IV with osteolysis, an arthrotomy with open debridement may be required. The surgical therapy can be supported with the application of local antibiotics.
Redon drainage is left in situ until the next irrigation is performed, control of wound and laboratory results, passive exercises, physiotherapy, systemic antibiotic therapy.
Between 2008 and 2013, we treated 13 patients with an infection after replacement of the ACL. In all cases, complete healing was achieved. In 4 cases, the graft was resected. In 2 patients, arthrofibrosis developed and arthrolysis was required.
对膝关节及供区进行清创和冲洗,以减少细菌数量,并清除前交叉韧带(ACL)置换术后感染病例中的细菌酶和炎性细胞因子。
确诊感染、疑似感染。
麻醉风险高。
ACL重建术后感染的治疗取决于Gächter所描述的不同阶段。在I期和II期,对所有腔室进行关节镜清创和冲洗(约10升)。手术期间获取多份活检样本进行微生物分析。术后立即开始广谱抗生素治疗。一旦了解细菌的耐药性,可根据结果更改抗生素治疗方案。当疼痛、肿胀、CRP或白细胞持续升高时,重复进行关节镜冲洗。在III期,进行完整的关节镜滑膜切除术。如果移植物完整,将其留在原位。如果移植物功能不全、隧道位置不当或持续感染,则进行切除。当骨隧道受到影响时,应进行清创。在IV期伴有骨质溶解时,可能需要进行切开清创术。可应用局部抗生素辅助手术治疗。
保留Redon引流管直至下次冲洗,观察伤口和实验室检查结果,进行被动运动、物理治疗、全身抗生素治疗。
2008年至2013年期间,我们治疗了13例ACL置换术后感染患者。所有病例均实现完全愈合。4例患者的移植物被切除。2例患者发生关节纤维化,需要进行关节松解术。