Aboshiha Jonathan
Moorfields Eye Hospital, and UCL Institute of Ophthalmology, London, UK.
Practitioner. 2013 Nov-Dec;257(1766):25-8, 3.
It is important to be vigilant for retained foreign bodies as a cause of recalcitrant bacterial conjunctivitis, even in the absence of foreign body sensation. A relapsing-remitting history should prompt referral to an ophthalmology department. All patients presenting with a red eye should be asked specifically about contact lens wear, and causes of conjunctivitis other than those bacterial in nature--such as viral and chlamydial infections or allergy--should be borne in mind. Contact lens wear may cause ocular complications, ranging from mild dry eye symptoms to contact lens-associated microbial keratitis, which is an ophthalmic emergency. Contact lens-associated corneal infections caused by Pseudomonas aeruginosa, which can rapidly penetrate the cornea, or Acanthamoeba can be severe and sight threatening. All patients with a history of contact lens wear and red flag symptoms such as eye pain, redness, reduction or change in vision, corneal epithelial defect, discharge, foreign body sensation or failure to respond to antibiotics should be referred for an urgent ophthalmic review. Retained contact lenses are known to cause several ocular complications, such as giant papillary conjunctivitis and ulcerative keratitis which may threaten corneal penetration. Lid eversion may reveal a hidden sub-tarsal contact lens. Use of fluorescein may also allow visualisation of any corneal epithelial defect. A careful slit lamp examination by an ophthalmologist is required to exclude this critical finding definitively.
即使没有异物感,对于顽固性细菌性结膜炎的病因,也要警惕是否存在残留异物。病情复发缓解的病史应促使患者转诊至眼科。所有出现眼红的患者都应被特别询问是否佩戴隐形眼镜,并且应考虑除细菌性结膜炎之外的其他病因,如病毒和衣原体感染或过敏。佩戴隐形眼镜可能会导致眼部并发症,从轻度干眼症状到与隐形眼镜相关的微生物性角膜炎,后者是一种眼科急症。由铜绿假单胞菌(可迅速穿透角膜)或棘阿米巴引起的与隐形眼镜相关的角膜感染可能很严重并威胁视力。所有有佩戴隐形眼镜史且出现眼痛、眼红、视力下降或改变、角膜上皮缺损、分泌物、异物感或对抗生素无反应等警示症状的患者都应转诊至眼科进行紧急检查。已知残留的隐形眼镜会导致多种眼部并发症,如巨大乳头性结膜炎和溃疡性角膜炎,这可能会威胁到角膜穿孔。翻转眼睑可能会发现隐藏在睑板下的隐形眼镜。使用荧光素也可能有助于观察到任何角膜上皮缺损。眼科医生需要进行仔细的裂隙灯检查以明确排除这一关键发现。