Gee Christopher, Tandon Tarang, Avasthi Adish, Jerwood Susie, Rao Biyyam M, Cavanagh Simon
Specialist Registrar, Trauma and Orthopaedics, Western Sussex Hospitals National Health Service Foundation Trust, St. Richards Hospital, Chichester, West Sussex, United Kingdom.
Specialist Registrar, Trauma and Orthopaedics, Western Sussex Hospitals National Health Service Foundation Trust, St. Richards Hospital, Chichester, West Sussex, United Kingdom.
J Foot Ankle Surg. 2014 Mar-Apr;53(2):216-8. doi: 10.1053/j.jfas.2013.12.019.
We present the case of a healthy 18-year-old female who presented with history of an acute onset, painful, swollen right ankle joint. Microbiologic samples from the ankle aspirate grew Neisseria meningitidis. She had had no previous contact with a patient with meningitis nor any existing or preceding clinical symptoms of meningitis. She was treated with surgical drainage with mini-open arthrotomy and a repeat washout at 48 hours. The identification of the organism was expedited using the Analytical Profiling Index (bioMérieux UK, Basingstoke, UK). Our patient was treated with 2 weeks of third-generation cephalosporin antibiotics. At the final follow-up visit, the inflammatory markers had returned to normal, with a normal ankle joint and no evidence of long-term sequelae of septic arthritis. Primary septic arthritis with N. meningitidis is exceptionally rare in the adult population and has been most often reported in the knee. To the best of our knowledge, this is the first reported case of primary septic arthritis of the native adult ankle joint in a healthy individual due to N. meningitides that was diagnosed and treated appropriately with no residual sequelae of the disease.
我们报告一例18岁健康女性病例,该患者右踝关节急性起病,疼痛、肿胀。踝关节穿刺液的微生物样本培养出脑膜炎奈瑟菌。她既往未曾接触过脑膜炎患者,也没有任何现有的或先前的脑膜炎临床症状。她接受了小切口关节切开术的手术引流,并在48小时后再次冲洗。使用分析谱指数(英国生物梅里埃公司,英国贝辛斯托克)加快了病原体的鉴定。我们的患者接受了两周的第三代头孢菌素抗生素治疗。在最后一次随访时,炎症标志物已恢复正常,踝关节正常,没有脓毒性关节炎长期后遗症的迹象。成人原发性脑膜炎奈瑟菌脓毒性关节炎极为罕见,最常报道于膝关节。据我们所知,这是首例在健康个体中因脑膜炎奈瑟菌导致的成人天然踝关节原发性脓毒性关节炎病例,该病例得到了恰当的诊断和治疗,且无疾病残留后遗症。