默认通过股动脉入路进行经皮冠状动脉介入治疗(PCI)的患者,其桡动脉操作者发生血管入路部位并发症的风险较高。

Patients undergoing PCI from the femoral route by default radial operators are at high risk of vascular access-site complications.

机构信息

Department of Cardiology, University Hospital of Wales, Cardiff, United Kingdom.

出版信息

EuroIntervention. 2014 Feb;9(10):1189-94. doi: 10.4244/EIJV9I10A200.

Abstract

AIMS

Radial artery (RA) access for PCI has a lower incidence of vascular access-site (VAS) complications than the femoral artery (FA) approach. However, even for default radial operators certain patients are intervened upon from the FA. We examined the demographics and incidence of VAS complications when default radial operators resort to the FA for PCI.

METHODS AND RESULTS

The demographics and VAS complications were compared by access site retrospectively for all PCI cases performed by default radial operators (n=1,392). A modified ACUITY trial definition of major VAS complication was used. FA puncture occurred in 25.2% (351/1,392) of cases. Patients were more likely to be female, older and weigh less than patients undergoing PCI from the RA. The FA procedure was likely to be more complex with larger sheaths, more left main stem, graft and multivessel intervention, and there was a greater proportion of emergency cases. Despite increased case complexity, glycoprotein inhibitors were used less frequently in femoral cases (26.5% vs. 36.8%, p<0.001). A VAS complication occurred in 12.5% (44/351) of cases.

CONCLUSIONS

The risk factors for access-site bleeding are disproportionately high in the population requiring FA puncture by default radial operators, and as a result such patients have a high rate of vascular access-site complications.

摘要

目的

经皮冠状动脉介入治疗(PCI)中桡动脉(RA)入路与股动脉(FA)入路相比,血管入路部位(VAS)并发症的发生率较低。然而,即使对于默认桡动脉操作者,某些患者仍需要从 FA 入路进行干预。我们检查了当默认桡动脉操作者需要进行 PCI 时,其采用 FA 入路的患者特征和 VAS 并发症的发生率。

方法和结果

我们回顾性比较了所有由默认桡动脉操作者进行的 PCI 病例(n=1,392)的入路部位和 VAS 并发症。采用改良的 ACUITY 试验中 VAS 并发症的主要定义。25.2%(351/1,392)的病例采用 FA 穿刺。与接受 RA 入路 PCI 的患者相比,FA 穿刺患者更可能为女性、年龄更大且体重更轻。FA 操作更可能更复杂,需要更大的鞘管、更多的左主干、搭桥和多血管介入,且急诊病例比例更高。尽管病例复杂性增加,但在股动脉病例中使用糖蛋白抑制剂的频率较低(26.5%比 36.8%,p<0.001)。12.5%(44/351)的病例发生 VAS 并发症。

结论

在需要默认桡动脉操作者进行 FA 穿刺的人群中,血管入路部位出血的危险因素不成比例地高,因此这些患者 VAS 并发症的发生率很高。

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