Circadian rhythm of apical Na-channels and Na-transport in rabbit distal colon.
作者信息
Clauss W, Dürr J E, Krattenmacher R, Hörnicke H, Van Driessche W
机构信息
Institut für Veterinärphysiologie, Freie Universität Berlin, Federal Republic of Germany.
出版信息
Experientia. 1988 Jul 15;44(7):608-10. doi: 10.1007/BF01953312.
PMID:2456225
Abstract
In vivo and in vitro studies showed that electrogenic sodium transport in rabbit distal colon is modulated by aldosterone. It varies in a circadian rhythm; the external synchronizer is the light-dark cycle. The site of regulation was found to be in the apical membrane of colonic epithelial cells, in which the number of conducting sodium-channels is increased by aldosterone.
摘要
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