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乳腺癌激素辅助治疗的皮肤不良反应:1例阿那曲唑治疗后局部荨麻疹性血管炎病例及文献综述

Cutaneous adverse effects of hormonal adjuvant therapy for breast cancer: a case of localised urticarial vasculitis following anastrozole therapy and a review of the literature.

作者信息

Bock Vanessa L, Friedlander Michael, Waring Dale, Kossard Steven, Wood Glenda K

机构信息

Brien Walder Department of Dermatology, Prince of Wales Hospital, Sydney, New South Wales, Australia.

出版信息

Australas J Dermatol. 2014 Nov;55(4):282-5. doi: 10.1111/ajd.12110. Epub 2013 Dec 2.

Abstract

Hormonal therapy with either tamoxifen or aromatase inhibitors is commonly used to treat women with breast cancer in both the adjuvant and recurrent disease setting. Cutaneous adverse reactions to these drugs have been rarely reported in the literature. We report an unusual case of urticarial vasculitis following the aromatase inhibitor anastrozole that localised to the unilateral trunk and mastectomy scar, and review the literature on the cutaneous adverse effects of hormonal therapy for breast cancer.

摘要

他莫昔芬或芳香化酶抑制剂的激素疗法常用于辅助治疗和复发性疾病情况下的乳腺癌女性患者。这些药物的皮肤不良反应在文献中鲜有报道。我们报告了一例使用芳香化酶抑制剂阿那曲唑后出现的荨麻疹性血管炎罕见病例,病变局限于单侧躯干和乳房切除瘢痕,并回顾了关于乳腺癌激素治疗皮肤不良反应的文献。

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