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避免人工瓣膜与患者不匹配的策略:主动脉根部扩大。

Strategy to avoid patient-prosthesis mismatch: aortic root enlargement.

作者信息

Srivastava Dharmendra Kumar, Sanki Prokash, Bhattacharya Subhankar, Siddique Javed Veqar

机构信息

Department of Cardiothoracic and Vascular Surgery, S.S.K.M. Hospital, Institute of Postgraduate Medical Education and Research, Kolkata, West Bengal, India.

出版信息

Asian Cardiovasc Thorac Ann. 2014 Feb;22(2):137-41. doi: 10.1177/0218492312469117. Epub 2013 Jul 9.

Abstract

BACKGROUND

The choice of a valve with an effective orifice area matching the body surface area and providing efficient hemodynamics is an important factor affecting mortality and morbidity in patients undergoing aortic valve replacement.

PATIENTS AND METHODS

Our preventative strategy was to implant a larger prosthetic valve by aortic root enlargement using the Nunez procedure in 17 patients between February 2010 and January 2011. The decision to enlarge the aortic root was taken when the 19-mm sizer could not be negotiated easily through the aortic root, or on the basis of body surface area of the patient or type of prosthesis available.

RESULTS

Postoperative reductions in peak and mean pressure gradients across aortic valve of 12.8-16.5 and 10.2-12.6 mm Hg, respectively, were observed. Postoperative effective orifice areas of the aortic valves were 1.1-1.5 cm(2). By upsizing the aortic valve, we were able to eliminate patient-prosthesis mismatch in 5 patients, and reduce severe patient-prosthesis mismatch to moderate in 11.

CONCLUSION

Aortic root enlargement is a safe procedure. Therefore, cardiac surgeons should not be reluctant to enlarge the aortic root with an autologous pericardial patch to permit implantation of an adequate size of aortic valve prosthesis, with minimal additional aortic crossclamp time and no added cost.

摘要

背景

选择有效瓣口面积与体表面积相匹配并能提供高效血流动力学的瓣膜,是影响主动脉瓣置换术患者死亡率和发病率的重要因素。

患者与方法

我们的预防策略是在2010年2月至2011年1月期间,对17例患者采用努涅斯手术通过扩大主动脉根部植入更大的人工瓣膜。当19毫米的测量器无法轻松通过主动脉根部,或根据患者的体表面积或可用的假体类型决定扩大主动脉根部。

结果

观察到术后主动脉瓣跨瓣峰值和平均压力梯度分别降低了12.8 - 16.5毫米汞柱和10.2 - 12.6毫米汞柱。术后主动脉瓣的有效瓣口面积为1.1 - 1.5平方厘米。通过加大主动脉瓣尺寸,我们能够消除5例患者的人工瓣膜-患者不匹配,并将11例严重的人工瓣膜-患者不匹配减轻为中度。

结论

主动脉根部扩大术是一种安全的手术。因此,心脏外科医生不应不愿用自体心包补片扩大主动脉根部,以允许植入足够尺寸的主动脉瓣假体,同时尽量减少额外的主动脉阻断时间且不增加成本。

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