Deng Nan-Nan, Sun Jian, Wang Wei, Ju Xiao-Jie, Xie Rui, Chu Liang-Yin
School of Chemical Engineering and ‡State Key Laboratory of Polymer Materials Engineering and Collaborative Innovation Center for Biomaterials Science and Technology, Sichuan University , Chengdu, Sichuan 610065, China.
ACS Appl Mater Interfaces. 2014 Mar 26;6(6):3817-21. doi: 10.1021/am500563z. Epub 2014 Mar 5.
Controllable one-to-one coalescence of surfactant-stabilized nanoliter water drops is successfully achieved from wetting-induced drop engulfing in microfluidics by surrounding one of the drops with a thin layer of immiscible wetting fluid. This wetting layer can spread over the other drop to drain away the liquid film between the two drops, thereby inducing coalescence. This innovative approach is totally spontaneous and highly potential in a myriad of fields, such as quantitative analysis, microreaction, and high-throughput injection. To demonstrate this potential, we successfully perform the drop-coalescence-triggered microreaction in microchannels for pH indicator and syntheses of functional materials including micro- and nanoparticles.
通过在微流体中利用不混溶的润湿流体薄层围绕其中一个液滴，由润湿诱导的液滴吞没成功实现了表面活性剂稳定的纳升水滴的可控一对一聚并。该润湿层可在另一液滴上扩散以排干两液滴之间的液膜，从而引发聚并。这种创新方法完全是自发的，在诸如定量分析、微反应和高通量注射等众多领域具有巨大潜力。为了证明这种潜力，我们在微通道中成功进行了用于pH指示剂的液滴聚并触发的微反应以及包括微米和纳米颗粒在内的功能材料的合成。
