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支气管哮喘患者的三维上气道评估

Three-dimensional upper-airway assessment in patients with bronchial asthma.

作者信息

Bandeira Alexandre Marcos, Oltramari-Navarro Paula Vanessa Pedron, de Lima Navarro Ricardo, de Castro Ferreira Conti Ana Cláudia, de Almeida Marcio Rodrigues, Fernandes Karen Barros Parron

机构信息

a  Former graduate student, Orthodontic Department, University of North Parana (UNOPAR), Londrina, Brazil.

出版信息

Angle Orthod. 2014 Mar;84(2):254-9. doi: 10.2319/030113-176.

DOI:10.2319/030113-176
PMID:24601628
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8673804/
Abstract

OBJECTIVE

To assess the upper airway (UAW) total volume (TV), the nasopharyngeal narrowest area (NNA), and the oropharyngeal narrowest area (ONA) in patients with bronchial asthma.

MATERIALS AND METHODS

The sample consisted of 52 patients divided into two groups: the control group (n  =  26; mean age  =  14.85 years), which consisted of patients not suffering from bronchial asthma; and the asthmatic group (n  =  26; mean age  =  16.65 years), which consisted of patients with bronchial asthma. To assess UAW-related variables (TV, NNA, and ONA), cone-beam computed tomography scans of the patients were evaluated by means of the Dolphin Imaging software 11.5. All measurements were repeated after 30 days, and the results were submitted to reliability tests by means of the intraclass correlation coefficient and the Bland-Altman agreement test. The values obtained for TV, NNA, and ONA for each group were compared by using Student's t-test for independent samples (5% level of significance).

RESULTS

The results showed that the groups were matched concerning gender, cephalometric characteristics, and type of malocclusion. The asthmatic group had significantly lower TV (P  =  .01) and ONA (P  =  .007) than the control group. However, no significant difference was observed for NNA between the groups (P  =  .54).

CONCLUSIONS

Bronchial asthma may be a determining factor for the reduction of UAW dimensions, as patients with asthma showed significant reductions in TV and ONA dimensions.

摘要

目的

评估支气管哮喘患者的上气道(UAW)总体积(TV)、鼻咽最窄面积(NNA)和口咽最窄面积(ONA)。

材料与方法

样本包括52例患者,分为两组:对照组(n = 26;平均年龄 = 14.85岁),由未患支气管哮喘的患者组成;哮喘组(n = 26;平均年龄 = 16.65岁),由支气管哮喘患者组成。为评估与UAW相关的变量(TV、NNA和ONA),通过Dolphin Imaging软件11.5对患者的锥形束计算机断层扫描进行评估。所有测量在30天后重复进行,结果通过组内相关系数和Bland-Altman一致性检验进行可靠性测试。使用独立样本的Student's t检验(显著性水平为5%)比较每组获得的TV、NNA和ONA值。

结果

结果显示两组在性别、头影测量特征和错牙合类型方面相匹配。哮喘组的TV(P = .01)和ONA(P = .007)显著低于对照组。然而,两组之间的NNA未观察到显著差异(P = .54)。

结论

支气管哮喘可能是UAW尺寸减小的一个决定性因素,因为哮喘患者的TV和ONA尺寸显著减小。