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将姑息治疗融入重症监护:一项质量改进研究。

Integrating Palliative Care into Critical Care: A Quality Improvement Study.

作者信息

Hsu-Kim Cynthia, Friedman Tara, Gracely Edward, Gasperino James

机构信息

Department of Medicine, Division of Internal Medicine, Drexel University College of Medicine, Philadelphia, PA, USA.

Vitas Palliative Care Solutions, Philadelphia, PA, USA.

出版信息

J Intensive Care Med. 2015 Sep;30(6):358-64. doi: 10.1177/0885066614523923. Epub 2014 Mar 5.

Abstract

BACKGROUND

Many terminally ill patients experience an increasing intensity of medical care, an escalation frequently not consistent with their preferences. In 2009, formal palliative care consultation (PCC) was integrated into our medical intensive care unit (ICU). We hypothesized that significant differences in clinical and economic outcomes exist between ICU patients who received PCC and those who did not.

METHODS

We reviewed ICU admissions between July and October 2010, identified 41 patients who received PCC, and randomly selected 80 patients who did not. We measured clinical outcomes and economic variables associated with patients' ICU courses.

RESULTS

Patients in the PCC group were older (average 64 years, standard deviation [SD] 19.2 vs 55.6 years, SD 14.5; P = .021) and sicker (median Acute Physiology and Chronic Health Evaluation IV score 85.5, interquartile range [IQR] 60.5-107.5 vs 60, IQR 39.2-74.75; P < .001) than the non-PCC controls. PCC patients received significantly more total days of ICU care on average (8 days, IQR 4-15 vs 4 days, IQR 2-7; P < .001), had more ICU admissions, and were more likely to die during their ICU stay (64.3% vs 12.5%, P < .001). Median total hospital charges per patient attributable to ICU care were higher in the PCC group than in the controls (US$315,493, IQR US$156,470-US$486,740 vs US$116,934, IQR US$54,750-US$288,660; P < .001). After we adjusted for ICU length of stay, we found that median ICU charges per day per patient did not differ significantly between the groups (US$37,463, IQR US$27,429-US$56,230 vs US$41,332, IQR US$30,149-US$63,288; P = .884). Median time to PCC during the ICU stay was 7 days (IQR 2-14.5 days).

CONCLUSIONS

Patients who received PCC had higher disease acuity, longer ICU lengths of stay, and higher ICU mortality than controls. "Trigger" programs in the ICU may improve utilization of PCC services, improve patient comfort, and reduce invasive, often futile end-of-life care.

摘要

背景

许多晚期患者接受的医疗护理强度不断增加,这种升级往往与他们的偏好不一致。2009年,正式的姑息治疗咨询(PCC)被纳入我们的医学重症监护病房(ICU)。我们假设接受PCC的ICU患者与未接受PCC的患者在临床和经济结果方面存在显著差异。

方法

我们回顾了2010年7月至10月期间的ICU入院情况,确定了41名接受PCC的患者,并随机选择了80名未接受PCC的患者。我们测量了与患者ICU病程相关的临床结果和经济变量。

结果

PCC组患者比非PCC对照组患者年龄更大(平均64岁,标准差[SD]19.2,而对照组为55.6岁,SD 14.5;P = 0.021)且病情更严重(急性生理与慢性健康状况评估IV评分中位数85.5,四分位间距[IQR]60.5 - 107.5,而对照组为60,IQR 39.2 - 74.75;P < 0.001)。PCC患者平均接受ICU护理的总天数显著更多(8天,IQR 4 - 15,而对照组为4天,IQR 2 - 7;P < 0.001),ICU入院次数更多,且在ICU住院期间死亡的可能性更大(64.3%对12.5%,P < 0.001)。PCC组每位患者因ICU护理产生的医院总费用中位数高于对照组(315,493美元,IQR 156,470 - 486,740美元,而对照组为116,934美元,IQR 54,750 - 288,660美元;P < 0.001)。在我们对ICU住院时间进行调整后,我们发现两组之间每位患者每天的ICU费用中位数没有显著差异(37,463美元,IQR 27,429 - 56,230美元,而对照组为41,332美元,IQR 30,149 - 63,288美元;P = 0.884)。ICU住院期间接受PCC的中位时间为7天(IQR 2 - 14.5天)。

结论

接受PCC的患者比对照组患者疾病严重程度更高、ICU住院时间更长且ICU死亡率更高。ICU中的“触发”项目可能会提高PCC服务的利用率,改善患者舒适度,并减少侵入性的、往往徒劳的临终护理。

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