从多种肿瘤相关抗原产生多个细胞毒性T淋巴细胞表位。
Production of multiple CTL epitopes from multiple tumor-associated antigens.
作者信息
Morita Rena, Hirohashi Yoshihiko, Nakatsugawa Munehide, Kanaseki Takayuki, Torigoe Toshihiko, Sato Noriyuki
机构信息
Department of Pathology, Sapporo Medical University School of Medicine, Sapporo, Japan.
出版信息
Methods Mol Biol. 2014;1139:345-55. doi: 10.1007/978-1-4939-0345-0_28.
PMID:24619692
Abstract
Identification of antigenic peptides derived from tumor-associated antigens (TAA) enables cancer vaccine therapy using antigenic peptides. Here, we summarize the design of antigenic peptides and induction of cytotoxic T lymphocytes (CTL) using antigenic peptides and validation of CTL.
摘要
鉴定源自肿瘤相关抗原（TAA）的抗原肽能够实现使用抗原肽进行癌症疫苗治疗。在此，我们总结抗原肽的设计、使用抗原肽诱导细胞毒性T淋巴细胞（CTL）以及CTL的验证。
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