巨大渗出性视网膜脱离继发于 von Hippel-Lindau 综合征视网膜血管瘤的光动力疗法。

Massive exudative retinal detachment following photodynamic therapy for retinal hemangioma in von Hippel-Lindau Syndrome.

机构信息

Department of Ophthalmology, the 2nd Xiangya Hospital, Central South University, Changsha, PR China.

出版信息

Photodiagnosis Photodyn Ther. 2014 Jun;11(2):250-3. doi: 10.1016/j.pdpdt.2014.02.013. Epub 2014 Mar 13.

DOI:10.1016/j.pdpdt.2014.02.013

Abstract

Photodynamic therapy (PDT) is a common treatment on retinal capillary hemangioma. We applied PDT to a patient with von Hippel-Lindau(VHL) syndrome and she developed severe massive exudative retinal detachment the next day, which is a rare complication for PDT. After intraocular anti-VEGF agent and peribulbar dexamethasone several times to the patient, her subretinal fluid disappeared and hemangiomas atrophied. Treatment with Anti-VEGF agent and corticosteroid is effective for such complication.

摘要

光动力疗法（PDT）是治疗视网膜毛细血管瘤的常用方法。我们对一名患有 von Hippel-Lindau（VHL）综合征的患者进行了 PDT 治疗，次日她发生了严重的大量渗出性视网膜脱离，这是 PDT 的罕见并发症。我们对患者进行了多次眼内抗 VEGF 药物和球旁地塞米松治疗后，她的视网膜下液消失，血管瘤萎缩。抗 VEGF 药物和皮质类固醇治疗对这种并发症有效。