与使用传统含氟牙膏和低氟牙膏相关的牙菌斑氟浓度。
Plaque fluoride concentrations associated to the use of conventional and low-fluoride dentifrices.
作者信息
Pessan Juliano Pelim, Manarelli Michele Mauricio, Kondo Karina Yuri, de Italiani Flávia Moraes, Kobayashi Cláudia Ayumi Nakai, Whitford Gary Milton, Buzalaf Marília Afonso Rabelo
出版信息
Am J Dent. 2013 Dec;26(6):347-50.
PURPOSE
This double-blind, crossover study evaluated whole plaque fluoride concentration (F), as well as whole plaque calcium concentrations (Ca) after brushing with a placebo (PD - fluoride free), low-fluoride (LFD, 513 microg F/g) and conventional (CD, 1,072 microg F/g) dentifrices.
METHODS
Children (n=20) were randomly assigned to brush twice daily with one of the dentifrices, during 7 days. On the 7th day, samples were collected at 1 and 12 hours after brushing. F and Ca were analyzed with an ion-selective electrode and with the Arsenazo III method, respectively. Data were analyzed by ANOVA, Tukey's test and by Pearson correlation coefficient (P< 0.05).
RESULTS
The use of the fluoridated dentifrices significantly increased plaque [F]s 1 hour after brushing when compared to PD, returning to baseline levels 12 hours after. Positive and significant correlations were found between plaque [F] and (Ca) under most of the conditions evaluated. The mean increase in plaque [F] observed 1 hour after brushing with the CD were only about 47% higher than those obtained for the LFD. The use of a LFD promotes proportionally higher increases in plaque [F] when compared to a CD. Plaque F concentrations were also shown to be dependent on plaque Ca concentrations.
目的
本双盲交叉研究评估了使用安慰剂牙膏（无氟牙膏，PD）、低氟牙膏（LFD，含氟量513微克/克）和传统含氟牙膏（CD，含氟量1,072微克/克）刷牙后全菌斑氟浓度（F）以及全菌斑钙浓度（Ca）。
方法
20名儿童被随机分配，每天使用其中一种牙膏刷牙两次，持续7天。在第7天，于刷牙后1小时和12小时采集样本。分别使用离子选择电极法和偶氮胂III法分析F和Ca。数据采用方差分析、Tukey检验和Pearson相关系数进行分析（P<0.05）。
结果
与使用PD相比，使用含氟牙膏刷牙1小时后菌斑[F]显著增加，12小时后恢复至基线水平。在大多数评估条件下，菌斑[F]与（Ca）之间存在正相关且具有显著性。使用CD刷牙1小时后观察到的菌斑[F]平均增加量仅比使用LFD高约47%。与CD相比，使用LFD可使菌斑[F]成比例地更高增加。菌斑F浓度也显示取决于菌斑Ca浓度。
Zotero 插件