Department of Health Policy, National Center for Child Health and Development, Tokyo, Japan.
BJOG. 2014 Mar;121 Suppl 1:40-8. doi: 10.1111/1471-0528.12630.
To investigate the risk of adverse pregnancy outcomes among adolescents in 29 countries.
Secondary analysis using facility-based cross-sectional data of the World Health Organization Multicountry Survey on Maternal and Newborn Health.
Twenty-nine countries in Africa, Latin America, Asia and the Middle East.
Women admitted for delivery in 359 health facilities during 2-4 months between 2010 and 2011.
Multilevel logistic regression models were used to estimate the association between young maternal age and adverse pregnancy outcomes.
Risk of adverse pregnancy outcomes among adolescent mothers.
A total of 124 446 mothers aged ≤24 years and their infants were analysed. Compared with mothers aged 20-24 years, adolescent mothers aged 10-19 years had higher risks of eclampsia, puerperal endometritis, systemic infections, low birthweight, preterm delivery and severe neonatal conditions. The increased risk of intra-hospital early neonatal death among infants born to adolescent mothers was reduced and statistically insignificant after adjustment for gestational age and birthweight, in addition to maternal characteristics, mode of delivery and congenital malformation. The coverage of prophylactic uterotonics, prophylactic antibiotics for caesarean section and antenatal corticosteroids for preterm delivery at 26-34 weeks was significantly lower among adolescent mothers.
Adolescent pregnancy was associated with higher risks of adverse pregnancy outcomes. Pregnancy prevention strategies and the improvement of healthcare interventions are crucial to reduce adverse pregnancy outcomes among adolescent women in low- and middle-income countries.
调查 29 个国家青少年不良妊娠结局的风险。
利用世界卫生组织多国孕产妇和新生儿健康调查的基于机构的横断面数据进行二次分析。
非洲、拉丁美洲、亚洲和中东的 29 个国家。
2010 年至 2011 年 2-4 个月期间在 359 个卫生机构分娩的妇女。
使用多水平逻辑回归模型估计年轻母亲年龄与不良妊娠结局之间的关联。
青少年母亲不良妊娠结局的风险。
共分析了 124446 名年龄≤24 岁的母亲及其婴儿。与 20-24 岁的母亲相比,10-19 岁的青少年母亲患有子痫前期、产褥期子宫内膜炎、全身感染、低出生体重、早产和严重新生儿疾病的风险更高。调整了胎龄和出生体重以及母亲特征、分娩方式和先天性畸形后,青少年母亲所生婴儿在医院内早期新生儿死亡的风险增加,但统计学上无显著性。此外,青少年母亲预防性使用子宫收缩药、剖宫产预防性使用抗生素和 26-34 周早产时使用产前皮质激素的覆盖率明显较低。
青少年妊娠与不良妊娠结局风险增加相关。预防妊娠策略和改善医疗干预措施对于减少中低收入国家青少年妇女的不良妊娠结局至关重要。