School of Pharmacy, University of Nizwa, P.B No 33, PO 616, Birkat Al Mouz, Nizwa, Oman.
Saudi Pharm J. 2014 Apr;22(2):163-9. doi: 10.1016/j.jsps.2013.07.006. Epub 2013 Aug 8.
Adverse drug reaction (ADR) monitoring and reporting requires a multidisciplinary approach and pharmacists have a major role to play in it. The present pilot study was conducted to assess the knowledge, attitude and behavior of community pharmacists to ADR related aspects in the Sultanate of Oman.
A self-administered questionnaire comprising of 21 questions were distributed to a random sample of pharmacists in two Governorates in the Sultanate of Oman. It assessed the knowledge of pharmacists on some of the selected basic aspects of drug safety. Further, the knowledge and attitude of community pharmacists toward ADR reporting and their behavior on ADR related aspects were assessed. A scoring scheme was used to estimate the median total score of participants for various parameters. Obtained scores were correlated with the demographics of the respondents.
A total of 107 community pharmacists participated in the survey giving a response rate of 72.3%. The responses of the pharmacists to the questions on the drug safety of individual drugs were incorrect for some important and practical questions. Consequently, total median score corresponding to these questions was 5 (Inter Quartile Range, IQR 2) out of a possible maximum score of 9, which was below the acceptable score. Total median score based on knowledge, attitude and behavior was 38 (IQR 8) out of a possible maximum of 50 which shows a moderate score. Lack of awareness on how to report an ADR and concern that the report may be wrong were the most common factors discouraging pharmacists from reporting ADRs. Qualification as well as years of experience were the only demographic parameters which had an influence on the score obtained by the pharmacists.
Even though the pharmacists had an acceptable knowledge, attitude and behavior on ADR reporting and related aspects, a good number of them had below than acceptable knowledge on drug safety related aspects of specific drugs. Educational programs have to be continued to generate awareness on how to report ADR and stimulate pharmacists' more active participation in the pharmacovigilance program. There is a genuine need to have training programs to improve the knowledge of pharmacists on ADR related aspects which are of benefit on a daily basis which could greatly have an impact on patient safety.
药物不良反应(ADR)监测和报告需要多学科方法,药剂师在其中发挥着重要作用。本初步研究旨在评估阿曼苏丹国社区药剂师在 ADR 相关方面的知识、态度和行为。
在阿曼苏丹国的两个省,向随机抽取的药剂师分发了一份包含 21 个问题的自填式问卷,评估药剂师对一些选定的药物安全基本方面的了解。此外,还评估了社区药剂师对 ADR 报告的知识和态度,以及他们在 ADR 相关方面的行为。使用评分方案来估计参与者在各种参数方面的中位数总分。将获得的分数与受访者的人口统计学数据相关联。
共有 107 名社区药剂师参与了调查,回应率为 72.3%。药剂师对个别药物药物安全的问题回答存在一些重要和实际问题的错误。因此,这些问题对应的总分中位数为 5(四分位距,IQR 2),满分 9 分,低于可接受分数。基于知识、态度和行为的总分中位数为 38(IQR 8),满分 50 分,表明处于中等水平。缺乏报告 ADR 的意识以及担心报告可能错误是阻碍药剂师报告 ADR 的最常见因素。资格和经验年限是唯一对药剂师得分有影响的人口统计学参数。
尽管药剂师在 ADR 报告和相关方面具有可接受的知识、态度和行为,但相当一部分药剂师对特定药物的药物安全相关方面的知识低于可接受水平。必须继续开展教育计划,提高药剂师对报告 ADR 的认识,激发他们更积极地参与药物警戒计划。有真正的需要开展培训计划,提高药剂师对 ADR 相关方面的知识,这对日常工作有益,可大大提高患者安全。