Prognostic gene mutations and distinct gene- and microRNA-expression signatures in acute myeloid leukemia with a sole trisomy 8.
作者信息
Becker Heiko, Maharry Kati, Mrózek Krzysztof, Volinia Stefano, Eisfeld Ann-Kathrin, Radmacher Michael D, Kohlschmidt Jessica, Metzeler Klaus H, Schwind Sebastian, Whitman Susan P, Mendler Jason H, Wu Yue-Zhong, Nicolet Deedra, Paschka Peter, Powell Bayard L, Carter Thomas H, Wetzler Meir, Kolitz Jonathan E, Carroll Andrew J, Baer Maria R, Caligiuri Michael A, Stone Richard M, Marcucci Guido, Bloomfield Clara D
机构信息
The Ohio State University Comprehensive Cancer Center, Columbus, OH, USA.
Alliance for Clinical Trials in Oncology Statistics and Data Center, Mayo Clinic, Rochester, MN, USA.
出版信息
Leukemia. 2014 Aug;28(8):1754-1758. doi: 10.1038/leu.2014.114. Epub 2014 Mar 21.
Abstract
摘要
相似文献
1
Prognostic gene mutations and distinct gene- and microRNA-expression signatures in acute myeloid leukemia with a sole trisomy 8.
Leukemia. 2014 Aug;28(8):1754-1758. doi: 10.1038/leu.2014.114. Epub 2014 Mar 21.
2
Trisomy 11 as an isolated abnormality in acute myeloid leukemia is associated with unfavorable prognosis but not with an NPM1 or KIT mutation.
Int J Clin Exp Pathol. 2011 Apr;4(4):371-7. Epub 2011 Apr 25.
3
Complex molecular genetic abnormalities involving three or more genetic mutations are important prognostic factors for acute myeloid leukemia.
Leukemia. 2016 Mar;30(3):545-54. doi: 10.1038/leu.2015.288. Epub 2015 Oct 21.
4
Secondary genetic lesions in acute myeloid leukemia with inv(16) or t(16;16): a study of the German-Austrian AML Study Group (AMLSG).
Blood. 2013 Jan 3;121(1):170-7. doi: 10.1182/blood-2012-05-431486. Epub 2012 Oct 31.
5
TET2 mutations improve the new European LeukemiaNet risk classification of acute myeloid leukemia: a Cancer and Leukemia Group B study.
J Clin Oncol. 2011 Apr 1;29(10):1373-81. doi: 10.1200/JCO.2010.32.7742. Epub 2011 Feb 22.
6
Adult acute myeloid leukemia with trisomy 11 as the sole abnormality is characterized by the presence of five distinct gene mutations: MLL-PTD, DNMT3A, U2AF1, FLT3-ITD and IDH2.
Leukemia. 2016 Nov;30(11):2254-2258. doi: 10.1038/leu.2016.196. Epub 2016 Jul 20.
7
AML with gain of chromosome 8 as the sole chromosomal abnormality (+8sole) is associated with a specific molecular mutation pattern including ASXL1 mutations in 46.8% of the patients.
Leuk Res. 2015 Mar;39(3):265-72. doi: 10.1016/j.leukres.2014.11.026. Epub 2014 Dec 16.
8
No correlation between trisomy 13 and FLT3 duplication in acute myeloid leukemia.
Cancer Genet Cytogenet. 2005 Jan 1;156(1):92-3. doi: 10.1016/j.cancergencyto.2004.04.007.
9
Implications of Mutation Profiling in Myeloid Malignancies-PART 1: Myelodysplastic Syndromes and Acute Myeloid Leukemia.
Oncology (Williston Park). 2018 Apr 15;32(4):e38-e44.
10
Hyperleukocytosis is associated with distinct genetic alterations and is an independent poor-risk factor in de novo acute myeloid leukemia patients.
Eur J Haematol. 2018 Jul;101(1):86-94. doi: 10.1111/ejh.13073. Epub 2018 May 22.
引用本文的文献
1
Outcomes and prognostic impact of trisomy 8 in acute myeloid leukemia patients treated with intensive chemotherapy.
Blood Cancer J. 2025 Aug 28;15(1):146. doi: 10.1038/s41408-025-01332-7.
2
Risk Stratification, Measurable Residual Disease, and Outcomes of AML Patients with a Trisomy 8 Undergoing Allogeneic Hematopoietic Stem Cell Transplantation.
Cancers (Basel). 2021 Nov 13;13(22):5679. doi: 10.3390/cancers13225679.
3
Acute Myelogenous Leukemia With Trisomy 8 and Concomitant Acquired Factor VII Deficiency.
J Investig Med High Impact Case Rep. 2019 Jan-Dec;7:2324709619872657. doi: 10.1177/2324709619872657.
4
Karyotyping and analysis of GNAS locus in intramuscular myxomas.
Oncotarget. 2017 Mar 28;8(13):22086-22094. doi: 10.18632/oncotarget.14986.
5
Flexible model-based clustering of mixed binary and continuous data: application to genetic regulation and cancer.
Nucleic Acids Res. 2017 Apr 20;45(7):e53. doi: 10.1093/nar/gkw1270.
6
Risk stratification of chromosomal abnormalities in chronic myelogenous leukemia in the era of tyrosine kinase inhibitor therapy.
Blood. 2016 Jun 2;127(22):2742-50. doi: 10.1182/blood-2016-01-690230. Epub 2016 Mar 22.
7
Impact of trisomy 8 on treatment response and survival of patients with chronic myelogenous leukemia in the era of tyrosine kinase inhibitors.
Leukemia. 2015 Nov;29(11):2263-6. doi: 10.1038/leu.2015.96. Epub 2015 Apr 14.
本文引用的文献
1
Integration of SNP and mRNA arrays with microRNA profiling reveals that MiR-370 is upregulated and targets NF1 in acute myeloid leukemia.
PLoS One. 2012;7(10):e47717. doi: 10.1371/journal.pone.0047717. Epub 2012 Oct 15.
2
Association of a microRNA/TP53 feedback circuitry with pathogenesis and outcome of B-cell chronic lymphocytic leukemia.
JAMA. 2011 Jan 5;305(1):59-67. doi: 10.1001/jama.2010.1919.
3
IDH mutations and trisomy 8 in myelodysplastic syndromes and acute myeloid leukemia.
Leukemia. 2010 Dec;24(12):2120-2. doi: 10.1038/leu.2010.213. Epub 2010 Sep 23.
4
BAALC and ERG expression levels are associated with outcome and distinct gene and microRNA expression profiles in older patients with de novo cytogenetically normal acute myeloid leukemia: a Cancer and Leukemia Group B study.
Blood. 2010 Dec 16;116(25):5660-9. doi: 10.1182/blood-2010-06-290536. Epub 2010 Sep 14.
5
Combined mutations of ASXL1, CBL, FLT3, IDH1, IDH2, JAK2, KRAS, NPM1, NRAS, RUNX1, TET2 and WT1 genes in myelodysplastic syndromes and acute myeloid leukemias.
BMC Cancer. 2010 Aug 2;10:401. doi: 10.1186/1471-2407-10-401.
6
IDH1 and IDH2 gene mutations identify novel molecular subsets within de novo cytogenetically normal acute myeloid leukemia: a Cancer and Leukemia Group B study.
J Clin Oncol. 2010 May 10;28(14):2348-55. doi: 10.1200/JCO.2009.27.3730. Epub 2010 Apr 5.
7
P53-induced microRNA-107 inhibits HIF-1 and tumor angiogenesis.
Proc Natl Acad Sci U S A. 2010 Apr 6;107(14):6334-9. doi: 10.1073/pnas.0911082107. Epub 2010 Mar 22.
8
Diagnosis and management of acute myeloid leukemia in adults: recommendations from an international expert panel, on behalf of the European LeukemiaNet.
Blood. 2010 Jan 21;115(3):453-74. doi: 10.1182/blood-2009-07-235358. Epub 2009 Oct 30.
9
MicroRNA signatures associated with cytogenetics and prognosis in acute myeloid leukemia.
Blood. 2008 Mar 15;111(6):3183-9. doi: 10.1182/blood-2007-07-098749. Epub 2008 Jan 10.
10
Trisomy 13 is strongly associated with AML1/RUNX1 mutations and increased FLT3 expression in acute myeloid leukemia.
Blood. 2007 Aug 15;110(4):1308-16. doi: 10.1182/blood-2007-02-072595. Epub 2007 May 7.
Zotero 插件