Zhang Liang, Yang Dejin, Yin Xinghua, Zhou Yixin
Department of Adult Joint Reconstructive Surgery, Beijing Jishuitan Hospital, Fourth Clinical College of Peking University, Jishuitan Orthopaedic College of Tsinghua University, 31 East Xinjiekou Street, Beijing, 100035, China.
Clin Rheumatol. 2014 Sep;33(9):1295-301. doi: 10.1007/s10067-014-2575-5. Epub 2014 Mar 21.
The purpose of this study is to investigate the clinical and radiographic results of total hip arthroplasty (THA) for the treatment of ankylosing spondylitis (AS) and to evaluate the effects of patient, prosthesis design, and surgical technique-related risk factors on postoperative functional results. We retrospectively reviewed the clinical and radiographic results of THA performed in 167 hips for 100 patients with AS. The average follow-up period was 54.8 months (range, 32-129 months). The hip passive-flexion arc averaged only 0 ° (0-40.0 °) before surgery, compared with 100.0 ° (85.0-110.0 °) at the most recent follow-up examination (P < 0.001). Multivariate regression demonstrated that significant variables for postoperative hip flexion were degree of preoperative flexion contracture, preoperative level of C-reactive protein, use of a 32-mm femoral head, and postoperative heterotopic ossification. In patients with AS with severe pain, limited motion and posture, as well as deformity, the overall outcomes after THA were found to be favorable with an encouraging midterm prosthetic survivorship, a low complication rate and a high level of patients' satisfaction. It seemed these patients were particularly predisposed to relative poor range of motion of the involved hips after THA which was closely related to patients' satisfaction. The surgeons should pay careful attention to all possible risk factors perioperatively and develop a comprehensive treatment regimen.
本研究的目的是调查全髋关节置换术(THA)治疗强直性脊柱炎(AS)的临床和影像学结果,并评估患者、假体设计以及与手术技术相关的风险因素对术后功能结果的影响。我们回顾性分析了100例AS患者167髋接受THA的临床和影像学结果。平均随访时间为54.8个月(范围32 - 129个月)。术前髋关节被动屈曲弧平均仅为0°(0 - 40.0°),而在最近一次随访检查时为100.0°(85.0 - 110.0°)(P < 0.001)。多因素回归分析显示,术后髋关节屈曲的显著变量包括术前屈曲挛缩程度、术前C反应蛋白水平、使用32mm股骨头以及术后异位骨化。对于有严重疼痛、活动和姿势受限以及畸形的AS患者,THA后的总体结果良好,中期假体生存率令人鼓舞,并发症发生率低,患者满意度高。似乎这些患者在THA后受累髋关节的活动范围相对较差,这与患者满意度密切相关。外科医生在围手术期应仔细关注所有可能的风险因素,并制定全面的治疗方案。