Thakur Neeta, Martin Melissa, Castellanos Elizabeth, Oh Sam S, Roth Lindsey A, Eng Celeste, Brigino-Buenaventura Emerita, Davis Adam, Meade Kelley, LeNoir Michael A, Farber Harold J, Thyne Shannon, Sen Saunak, Bibbins-Domingo Kirsten, Borrell Luisa N, Burchard Esteban G
Department of Medicine, Division of Pulmonary and Critical Care Medicine .
J Asthma. 2014 Sep;51(7):720-8. doi: 10.3109/02770903.2014.905593. Epub 2014 May 14.
African Americans are disproportionately burdened by asthma. We assessed the individual and joint contribution of socioeconomic status (SES) on asthma morbidity among African American youth.
We examined 686 African Americans (8-21 years) with asthma. To account for the joint effects of SES, a composite index was derived from maternal educational attainment, household income, and insurance status. Ordinal logistic regression was used to estimate the individual and joint effect of SES on asthma control. Models were adjusted for age, sex, controller medication use, in utero smoke exposure, family history of asthma, family history of rhinitis, breastfeeding, daycare attendance, and mold exposure.
Participants were classified as Poorly Controlled Asthma (40.8%), Partially Controlled Asthma (29.7%), or Controlled Asthma (30.2%). Of the individual SES indicators, low income was the strongest predictor of poor asthma control. Children with low income had worse asthma control than those with higher income (OR 1.39; 95% CI 0.92-2.12). The SES index ranged from 4-9. SES was associated with 17% increased odds of poor asthma control with each decrease in the index (95% CI 1.05-1.32). The SES index was associated with asthma-related symptoms, nocturnal awakenings, limited activity, and missed school days.
The negative effects of SES were observed along the entire socioeconomic gradient, and the adverse asthma outcomes observed in African American youth were not limited to the very poor. We also found that the SES index may be a more consistent and useful predictor of poor asthma outcomes than each indicator alone.
非裔美国人受哮喘影响的负担过重。我们评估了社会经济地位(SES)对非裔美国青少年哮喘发病率的个体及共同影响。
我们研究了686名患有哮喘的非裔美国人(8至21岁)。为了考量SES的共同影响,从母亲的教育程度、家庭收入和保险状况得出一个综合指数。采用有序逻辑回归来估计SES对哮喘控制的个体及共同影响。模型针对年龄、性别、控制药物使用、子宫内烟雾暴露、哮喘家族史、鼻炎家族史、母乳喂养、日托出勤情况和霉菌暴露进行了调整。
参与者被分类为哮喘控制不佳(40.8%)、部分控制(29.7%)或控制良好(30.2%)。在个体SES指标中,低收入是哮喘控制不佳的最强预测因素。低收入儿童的哮喘控制比高收入儿童更差(比值比1.39;95%置信区间0.92 - 2.12)。SES指数范围为4至9。SES指数每降低一点,哮喘控制不佳的几率增加17%(95%置信区间1.05 - 1.32)。SES指数与哮喘相关症状、夜间觉醒、活动受限和缺课天数有关。
在整个社会经济梯度上都观察到了SES的负面影响,并且在非裔美国青少年中观察到的不良哮喘结局并不局限于非常贫困的人群。我们还发现,SES指数可能比单独的每个指标更能一致且有效地预测不良哮喘结局。