生物活性玻璃颗粒填充复合材料：填料偶联和填料负载对某些物理性能的影响。

Bioactive glass particulate filler composite: Effect of coupling of fillers and filler loading on some physical properties.

机构信息

Department of Biomaterials Science & Turku Clinical Biomaterials Centre-TCBC, Institute of Dentistry, University of Turku, Lemminkäisenkatu 2, FI-20014 Turku, Finland.

出版信息

Dent Mater. 2014 May;30(5):570-7. doi: 10.1016/j.dental.2014.02.017. Epub 2014 Mar 18.

DOI:10.1016/j.dental.2014.02.017

PMID:24655591

Abstract

OBJECTIVES

The aim of this study was to investigate the effect of silanization of biostable and bioactive glass fillers in a polymer matrix on some of the physical properties of the composite.

METHODS

The water absorption, solubility, flexural strength, flexural modulus and toughness of different particulate filler composite resins were studied in vitro. Five different specimen groups were analyzed: A glass-free control, a non-silanized bioactive glass, a silanized bioactive glass, a non-silanized biostable glass and a silanized biostable glass groups. All of these five groups were further divided into sub-groups of dry and water-stored materials, both of them containing groups with 3wt%, 6wt%, 9wt% or 12wt% of glass particles (n=8 per group). The silanization of the glass particles was carried out with 2% of gamma-3-methacryloxyproyltrimethoxysilane (MPS). For the water absorption and solubility tests, the test specimens were stored in water for 60 days, and the percentages of weight change were statistically analyzed. Flexural strength, flexural modulus and toughness values were tested with a three-point bending test and statistically analyzed.

RESULTS

Higher solubility values were observed in non-silanized glass in proportion to the percentage of glass particles. Silanization, on the other hand, decreased the solubility values of both types of glass particles and polymer. While 12wt% non-silanized bioactive glass specimens showed -0.98wt% solubility, 12wt% silanized biostable glass specimens were observed to have only -0.34wt% solubility. The three-point bending results of the dry specimens showed that flexural strength, toughness and flexural modulus decreased in proportion to the increase of glass fillers. The control group presented the highest results (106.6MPa for flexural strength, 335.7kPA for toughness, 3.23GPa for flexural modulus), whereas for flexural strength and toughness, 12wt% of non-silanized biostable glass filler groups presented the lowest (70.3MPa for flexural strength, 111.5kPa for toughness). For flexural modulus on the other hand, 12wt% of silanized biostable glass filler group gave the lowest results (2.57GPa).

SIGNIFICANCE

The silanization of glass fillers improved the properties of the glass as well as the properties of the composite. Silanization of bioactive glass may protect the glass from leaching at early stage of water storage.

摘要

目的

本研究旨在探讨在聚合物基质中对生物稳定和生物活性玻璃填料进行硅烷化处理对复合材料某些物理性能的影响。

方法

体外研究了不同颗粒填料复合树脂的吸水率、溶解度、弯曲强度、弯曲模量和韧性。分析了五个不同的样本组：无玻璃对照组、非硅烷化生物活性玻璃、硅烷化生物活性玻璃、非硅烷化生物稳定玻璃和硅烷化生物稳定玻璃组。这五个组进一步分为干材料和水储存材料亚组，每个亚组包含 3wt%、6wt%、9wt%或 12wt%玻璃颗粒的组（每组 8 个）。玻璃颗粒的硅烷化处理采用 2%的γ-3-甲基丙烯酰氧基丙基三甲氧基硅烷（MPS）进行。对于吸水率和溶解度测试，将试件在水中储存 60 天，并对重量变化百分比进行统计分析。使用三点弯曲试验测试弯曲强度、弯曲模量和韧性值，并进行统计分析。

结果

非硅烷化玻璃的溶解度值随着玻璃颗粒百分比的增加而升高。另一方面，硅烷化处理降低了两种类型玻璃颗粒和聚合物的溶解度值。虽然 12wt%非硅烷化生物活性玻璃样品的溶解度为-0.98wt%，但 12wt%硅烷化生物稳定玻璃样品的溶解度仅为-0.34wt%。干燥试件的三点弯曲结果表明，弯曲强度、韧性和弯曲模量随玻璃填料的增加而降低。对照组表现出最高的结果（弯曲强度为 106.6MPa，韧性为 335.7kPa，弯曲模量为 3.23GPa），而对于弯曲强度和韧性，12wt%非硅烷化生物稳定玻璃填料组的结果最低（弯曲强度为 70.3MPa，韧性为 111.5kPa）。另一方面，对于弯曲模量，12wt%硅烷化生物稳定玻璃填料组给出的结果最低（2.57GPa）。