Taniyama K, Suzuki H, Hara T, Yokoyama S, Tahara E
Dept. of Pathology, Shizuoka General Hospital.
Gan No Rinsho. 1989 Jan;35(1):107-13.
A case of an ovarian, poorly differentiated, Sertoli-Leydig cell tumor in a 55-year-old woman is reported. The patient showed no virilization, but did show elevated serum alpha-fetoprotein (AFP) levels. The tumor, measuring 70 x 45 x 50 mm, consisted mainly of a diffuse proliferation of spindle cells. Among this proliferation, some tubules of Sertoli cells and groups of leydig cells were found. Immunoperoxidase studies, using anti-AFP, localized the AFP in the leydig cells.
报告了一例55岁女性的卵巢低分化支持-间质细胞瘤。患者未出现男性化表现,但血清甲胎蛋白(AFP)水平升高。肿瘤大小为70×45×50mm,主要由梭形细胞弥漫性增生组成。在这种增生中,发现了一些支持细胞小管和间质细胞群。使用抗AFP进行免疫过氧化物酶研究,将AFP定位在间质细胞中。