聚维酮碘引起的术后接触性皮炎：诊断难题。

Postsurgical contact dermatitis due to povidone iodine: a diagnostic dilemma.

作者信息

de la Cuadra-Oyanguren J, Zaragozá-Ninet V, Sierra-Talamantes C, Alegre de Miquel V

机构信息

Sección de Alergia cutánea, Servicio de Dermatología, Consorcio Hospital General Universitario de Valencia, Valencia, Spain.

出版信息

Actas Dermosifiliogr. 2014 Apr;105(3):300-4. doi: 10.1016/j.adengl.2012.11.028. Epub 2014 Mar 21.

DOI:10.1016/j.adengl.2012.11.028

PMID:24661954

Abstract

We present 7 cases of postsurgical contact dermatitis due to povidone iodine. The diagnosis was based on the clinical manifestations, the history of exposure, the site of the lesions, and the results of patch tests. This type of dermatitis can develop in the area of surgery or at distant sites exposed to povidone iodine during the surgical intervention. Patch tests with 10% povidone iodine in petrolatum were positive in all patients. Based on the results of the same tests in a control group, we recommend the use of petrolatum rather than water as the vehicle for the diagnosis of this form of contact dermatitis. Repeated open application tests with a commercially available solution of povidone iodine were negative. We conclude that the presence of the solution under occlusion during surgery is necessary both for the symptoms to develop and for the diagnosis to be made. This condition may be underdiagnosed.

摘要

我们报告了7例因聚维酮碘引起的术后接触性皮炎病例。诊断基于临床表现、接触史、皮损部位以及斑贴试验结果。这种类型的皮炎可发生在手术区域，或在手术干预期间接触聚维酮碘的远处部位。所有患者使用凡士林基质中10%聚维酮碘进行斑贴试验均呈阳性。基于对照组相同试验的结果，我们建议使用凡士林而非水作为诊断这种接触性皮炎的赋形剂。使用市售聚维酮碘溶液进行的反复开放性应用试验为阴性。我们得出结论，手术期间封闭状态下存在该溶液对于症状的出现和诊断的做出都是必要的。这种情况可能未得到充分诊断。