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[Ménétrieŕs disease associated with cytomegalovirus infection].

作者信息

Fernández Caamaño B, Ramos Boluda E, Martínez-Ojinaga Nodal E, Molina Arias M, Sarría Osés J, Prieto Bozano G

机构信息

Servicio de Gastroenterología, Hospital Universitario La Paz, Madrid, España.

Servicio de Gastroenterología, Hospital Universitario La Paz, Madrid, España.

出版信息

An Pediatr (Barc). 2015 Jan;82(1):e113-6. doi: 10.1016/j.anpedi.2014.02.019. Epub 2014 Mar 22.

Abstract

Menetrier's disease is a rare entity in children, characterized by a protein-losing gastroenteropathy with thickening of the gastric mucosa and generalized edema. The most common etiology is viral, and cytomegalovirus is the agent most frequently implicated. Unlike in the adult, it is a self-limited disorder with a good prognosis in children. Four patients (three boys and one girl) diagnosed with Ménétrier disease in the past five years were reviewed. The mean age at presentation was 28.7 months (range: 10-48 months). The most common clinical symptoms were fever, vomiting, and edema. Endoscopy showed thickened gastric folds and erosions in several stages. All patients had an associated gastric cytomegalovirus infection, and a favorable outcome, with resolution of the disorder,was observed within a few weeks.

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