Sadarmin Praveen P, Wong Kelvin Ck, Rajappan Kim, Bashir Yaver, Betts Timothy R
Department of Cardiology, Oxford Heart Centre, John Radcliffe Hospital, Oxford University Hospitals NHS Trust, Headington, Oxford OX3 9DU, UK.
Department of Cardiology, Oxford Heart Centre, John Radcliffe Hospital, Oxford University Hospitals NHS Trust, Headington, Oxford OX3 9DU, UK
Europace. 2014 Nov;16(11):1575-9. doi: 10.1093/europace/euu054. Epub 2014 Mar 25.
Primary prevention (PP) implantable cardioverter defibrillator (ICD) implant rates in the UK are below national targets and barriers to this are not well known. This study was designed to identify the stages along the referral pathway from general to specialist care that eligible patients reach and what proportion eventually receive an ICD.
A single institution database search was performed to identify all adults with severe left ventricular systolic dysfunction (left ventricular ejection fraction, LVEF≤35%), documented in the calendar year 2007. Medical records were assessed for age, heart failure aetiology, QRS duration, evidence of non-sustained ventricular tachycardia on Holter, electrophysiological study, and records of consultation with general physicians, cardiologists, and electrophysiologists (EPs) and reference to assessment of risk of sudden cardiac death and the role of ICD implantation. Three hundred twenty-six patients with LVEF ≤ 35% were identified from three electronic databases. Mean age was 72 ± 12 years. Seventy-two patients satisfied UK National Institute for Clinical Excellence guidelines for PP ICD implantation and 63 eligible for further screening. Of the 135 patients, 76 (56%) patients reviewed by a general cardiologist did not receive ICD implantation or referral for further assessment. When offered, ICD acceptance rate was high (35 vs. 3 patients who refused ICD). After seeing an EP, 8 of 47 (17%) patients were not offered ICD or further screening. The average age was 66.5 ± 6.2 years and no patient greater than 80 years had a PP ICD.
Failure to refer from the general physician to cardiology and from the cardiologist to EP is the principle reason for low PP ICD implant rates among eligible patients in the UK.
英国一级预防(PP)植入式心脏复律除颤器(ICD)的植入率低于国家目标,且对此的障碍尚不明确。本研究旨在确定符合条件的患者在从全科医疗转诊至专科医疗的过程中所能达到的阶段,以及最终接受ICD植入的患者比例。
通过单机构数据库搜索,确定2007日历年记录的所有严重左心室收缩功能障碍(左心室射血分数,LVEF≤35%)的成年人。评估病历中的年龄、心力衰竭病因、QRS时限、动态心电图上非持续性室性心动过速的证据、电生理研究,以及与全科医生、心脏病专家和电生理学家(EP)的会诊记录,以及关于心脏性猝死风险评估和ICD植入作用的参考资料。从三个电子数据库中识别出326例LVEF≤35%的患者。平均年龄为72±12岁。72例患者符合英国国家临床优化研究所PP ICD植入指南,63例有资格进行进一步筛查。在这135例患者中,76例(56%)经普通心脏病专家评估后未接受ICD植入或转诊进行进一步评估。当提供ICD时,接受率很高(35例接受ICD,3例拒绝)。在看过EP后,47例患者中有8例(17%)未被提供ICD或进一步筛查。平均年龄为66.5±6.2岁,没有年龄大于80岁的患者接受PP ICD。
在英国,符合条件的患者中PP ICD植入率低的主要原因是全科医生未转诊至心脏病科,以及心脏病专家未转诊至EP。