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男性性别对腹腔镜胆囊切除术结果的影响。

Male gender impact on the outcome of laparoscopic cholecystectomy.

作者信息

Bazoua George, Tilston Michael P

机构信息

General Surgery Department, Diana Princess of Wales Hospital, Grimsby, England DN33 2BA, UK.

Department of General Surgery, Diana Princess of Wales Hospital, Grimsby, England, UK.

出版信息

JSLS. 2014 Jan-Mar;18(1):50-4. doi: 10.4293/108680813X13693422518830.

Abstract

BACKGROUND AND OBJECTIVES

Our aim was to assess the impact of male gender on the outcomes of laparoscopic cholecystectomy by eliminating associated risk factors for conversion.

METHODS

A quantitative comparative study was set up on the background of our null hypothesis that male gender has no impact on the outcomes of laparoscopic cholecystectomy. We performed a retrospective study of 241 patients and recorded the duration of surgery, length of postoperative hospital stay, conversion rate, and procedure-specific complications. Risk factors for conversion were excluded. Inferential statistics were applied, and a 2-sided P value of < .05 was considered the cutoff point to indicate the amount of evidence against the null hypothesis. We used SPSS for Windows, version 12 (IBM, Armonk, New York). Parametric data were analyzed with the independent-samples t test, and nonparametric data were analyzed with the χ(2) test.

RESULTS

A total of 175 women (72.6%) and 66 men (27.4%) underwent laparoscopic cholecystectomy. The mean age was 51.4 ± 14.8 years for women and 55 ± 12.7 years for men (P = .08). Women had a higher body mass index (28.4 ± 4.5) than men (26.8 ± 3.5) (P < .005). There were no statistically significant differences in the conversion rate and perioperative morbidity rate. The conversion rate was 2.9% for women and 7.5% for men (P = .142); the morbidity rate was 10.2% and 12.1%, respectively (P = .66). The mean duration of surgery was longer in men, at 67.9 ± 27.8 minutes, than in women, at 56.5 ± 23.98 minutes (P < .002). Both genders had an equal length of postoperative hospital stay, with 1.9 ± 1.8 days for men and 1.9 ± 2.1 days for women (P = .8).

CONCLUSIONS

Male gender has no impact on the outcomes of laparoscopic cholecystectomy. Gender affects the duration of surgery. Larger-scale studies may disclose the factors responsible for variations in the operative time.

摘要

背景与目的

我们的目的是通过消除相关的中转危险因素来评估男性性别对腹腔镜胆囊切除术结局的影响。

方法

在我们的零假设(即男性性别对腹腔镜胆囊切除术结局无影响)的背景下开展了一项定量比较研究。我们对241例患者进行了回顾性研究,并记录了手术时长、术后住院时间、中转率及特定手术并发症。排除了中转的危险因素。应用了推断统计学方法,双侧P值<0.05被视为表明反对零假设的证据量的截断点。我们使用了Windows版SPSS 12.0(IBM公司,纽约州阿蒙克)。参数数据采用独立样本t检验进行分析,非参数数据采用χ²检验进行分析。

结果

共有175例女性(72.6%)和66例男性(27.4%)接受了腹腔镜胆囊切除术。女性的平均年龄为51.4±14.8岁,男性为55±12.7岁(P = 0.08)。女性的体重指数(28.4±4.5)高于男性(26.8±3.5)(P<0.005)。中转率和围手术期发病率无统计学显著差异。女性中转率为2.9%,男性为7.5%(P = 0.142);发病率分别为10.2%和12.1%(P = 0.66)。男性的平均手术时长更长,为67.9±27.8分钟,女性为56.5±23.98分钟(P<0.002)。男女术后住院时间相等,男性为1.9±1.8天,女性为1.9±2.1天(P = 0.8)。

结论

男性性别对腹腔镜胆囊切除术的结局无影响。性别影响手术时长。更大规模的研究可能会揭示导致手术时间差异的因素。

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