Dzikamunhenga R S, Wilberts B, Yaeger M, Burrough E, Hostetter J, Bender H, Larson W, Griffith R W
Avian Dis. 2013 Jun;57(2):188-91. doi: 10.1637/10320-080612-Reg.1.
Coccidiosis remains a significant threat to the welfare of game farm-reared pheasants in the United States. Although lasalocid has been demonstrated to be effective against pheasant specific coccidia, information regarding its safety in this species is lacking. The purpose of this study was to gather data on the safety of lasalocid when fed to Chinese ring-necked pheasants at one, two, and three times the recommended high dose of lasalocid used for prevention of coccidiosis in other poultry at three times the normal treatment period. Pheasant chicks (approximately 1 day-old; n = 160) were randomly blocked by sex into four treatment groups and given their respective diets continuously for 6 wk. No significant differences were observed in overall feed consumption, weight gain, feed conversion rates, clinical pathology measurements, or tissue gross and histopathologic evaluations between controls and treatment groups associated with lasalocid administration. Based on the results of this study it appears that lasalocid fed at the recommended rate of 125 ppm is safe in Chinese ring-necked pheasants.
在美国,球虫病仍然是对狩猎场饲养的雉鸡健康的重大威胁。尽管已证明拉沙洛西对雉鸡特定球虫有效,但缺乏关于其在该物种中安全性的信息。本研究的目的是收集在正常治疗期的三倍时间内,以用于预防其他家禽球虫病的推荐高剂量的一、二、三倍,将拉沙洛西喂给中国环颈雉时的安全性数据。雉鸡雏鸡(约1日龄;n = 160)按性别随机分为四个治疗组,并连续6周给予各自的日粮。在与拉沙洛西给药相关的对照组和治疗组之间,在总采食量、体重增加、饲料转化率、临床病理学测量或组织大体和组织病理学评估方面未观察到显著差异。基于本研究结果,以125 ppm的推荐剂量投喂拉沙洛西在中国环颈雉中似乎是安全的。