Chiu David T, Shapiro Nathan I, Sun Benjamin C, Mottley J Lawrence, Grossman Shamai A
Department of Emergency Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts.
Department of Emergency Medicine, Oregon Health and Science University, Portland, Oregon.
J Emerg Med. 2014 Jul;47(1):113-8. doi: 10.1016/j.jemermed.2014.01.018. Epub 2014 Mar 31.
Prior studies of admitted geriatric syncope patients suggest that diagnostic tests affect management < 5% of the time; whether this is true among all emergency department (ED) patients with syncope remains unclear.
To determine the diagnostic yield of routine testing in the hospital or after ED discharge among patients presenting to an ED with syncope.
A prospective, observational, cohort study of consecutive ED patients aged ≥ 18 years presenting with syncope was conducted. The four most commonly utilized tests (echocardiography, telemetry, ambulatory electrocardiography monitoring, and troponin) were studied. Interobserver agreement as to whether test results determined the etiology of the syncope was measured using kappa (κ) values.
Of 570 patients with syncope, 73 patients (8%; 95% confidence interval 7-10%) had studies that were diagnostic. One hundred fifty (26%) had echocardiography, with 33 (22%) demonstrating a likely etiology of the syncopal event, such as critical valvular disease or significantly depressed left ventricular function (κ = 0.75). On hospitalization, 330 (58%) patients were placed on telemetry, and 19 (3%) had worrisome dysrhythmias (κ = 0.66). There were 317 (55%) patients who had troponin levels drawn, of whom 19 (3%) had positive results (κ = 1); 56 (10%) patients were discharged with monitoring, with significant findings in only 2 (0.4%) patients (κ = 0.65).
Although routine testing is prevalent in ED patients with syncope, the diagnostic yield is relatively low. Nevertheless, some testing, particularly echocardiography, may yield critical findings. Current efforts to reduce the cost of medical care by eliminating nondiagnostic medical testing and increasing emphasis on practicing evidence-based medicine argue for more discriminate testing when evaluating syncope.
既往针对老年晕厥住院患者的研究表明,诊断性检查对治疗的影响不到5%;在所有急诊科(ED)晕厥患者中是否也是如此仍不清楚。
确定在急诊科就诊的晕厥患者在住院期间或出院后进行常规检查的诊断率。
对年龄≥18岁、连续就诊的急诊科晕厥患者进行一项前瞻性观察队列研究。研究了四种最常用的检查(超声心动图、遥测心电图、动态心电图监测和肌钙蛋白)。使用kappa(κ)值衡量观察者间关于检查结果是否能确定晕厥病因的一致性。
在570例晕厥患者中,73例(8%;95%置信区间7 - 10%)的检查具有诊断意义。150例(26%)患者接受了超声心动图检查,其中33例(22%)显示晕厥事件可能的病因,如严重瓣膜病或左心室功能明显降低(κ = 0.75)。住院期间,330例(58%)患者接受了遥测心电图检查,19例(3%)出现令人担忧的心律失常(κ = 0.66)。317例(55%)患者进行了肌钙蛋白水平检测,其中19例(3%)结果呈阳性(κ = 1);56例(10%)患者出院时接受了监测,只有2例(0.4%)患者有显著发现(κ = 0.65)。
虽然常规检查在急诊科晕厥患者中很普遍,但诊断率相对较低。然而,一些检查,特别是超声心动图检查,可能会得出关键结果。目前通过消除非诊断性医学检查来降低医疗成本以及越来越强调实施循证医学的努力表明,在评估晕厥时应进行更有针对性的检查。