Maurer T, Eiber M, Krause B J
Urologische Klinik und Poliklinik, Technische Universität München, Klinikum rechts der Isar, Ismaninger Straße 22, 81671, München, Deutschland,
Urologe A. 2014 Apr;53(4):469-83. doi: 10.1007/s00120-014-3440-5.
Since the introduction of combined radiologic-nuclear imaging procedures like PET/CT and PET/MRI, new and promising diagnostic tools in bladder and prostate cancer imaging are available to physicians. Although PET-based hybrid imaging in bladder cancer is currently utilized only in selected cases, an increase in PET imaging can be observed in prostate cancer due to the development of cancer-specific PET tracers. Especially novel ligands of prostate-specific membrane antigen (PSMA) exhibit great potential to effectively influence future staging of prostate cancer. However, before recommendations for implication in routine staging can be given, evaluation in the context of prospective multicenter clinical trials are mandatory.
自从引入PET/CT和PET/MRI等放射学-核医学联合成像检查程序以来,医生们在膀胱癌和前列腺癌成像方面有了新的、有前景的诊断工具。虽然基于PET的混合成像目前仅在膀胱癌的特定病例中使用,但由于癌症特异性PET示踪剂的发展,前列腺癌的PET成像有所增加。特别是前列腺特异性膜抗原(PSMA)的新型配体在有效影响未来前列腺癌分期方面具有巨大潜力。然而,在能够给出常规分期应用的建议之前,必须在前瞻性多中心临床试验的背景下进行评估。