位置血氧测定法筛查 HHT 中的肺动静脉畸形。

Positional oximetry to screen for pulmonary arteriovenous malformations in HHT.

机构信息

Division of Respiratory Medicine, Department of Paediatrics, The Hospital for Sick Children, Toronto, Canada.

Division of Respiratory Medicine, Department of Paediatrics, The Hospital for Sick Children, Toronto, Canada Physiology & Experimental Medicine, Research Institute, The Hospital for Sick Children, Toronto, Canada University of Toronto, Toronto, Canada.

出版信息

Thorax. 2014 Nov;69(11):1045. doi: 10.1136/thoraxjnl-2013-205028. Epub 2014 Apr 4.

DOI:10.1136/thoraxjnl-2013-205028

PMID:24706042

Abstract

Orthodeoxia has been described in patients with hereditary haemorrhagic telangiectasia (HHT) and pulmonary arteriovenous malformations (PAVM), but its usefulness in screening children for PAVMs is unknown. We show here that while oximetry is overall lower in children with significant PAVMs, supine and upright oximetry is of no additional diagnostic value indicating that positional oximetry is not a useful screening test for PAVMs.

摘要

体位性低氧血症已在遗传性出血性毛细血管扩张症（HHT）和肺动静脉畸形（PAVM）患者中被描述，但它在儿童 PAVM 筛查中的作用尚不清楚。我们在这里表明，虽然存在显著 PAVM 的儿童的血氧饱和度总体较低，但仰卧位和直立位血氧饱和度无额外诊断价值，表明体位血氧饱和度不是 PAVM 的有用筛查试验。