Aver'ianov Iu N, Nechkina N P, Vinogradova N V, Zakhidov A Ia
Zh Nevropatol Psikhiatr Im S S Korsakova. 1989;89(3):128-31.
Inborn analgesia (IA) is described in 3 members of a family: a 14 month-old girl, hel father and grandfather on the paternal line. Generalized indifference to pain and visceral analgesia with other senses intact was noted in all patients since birth. Profound reflexes, intellectual development, karyotype, motor and sensory nervous excitation propagation velocities, somatosensory evoked potentials were all normal. Notedly, the IA inheritance was found to be autosome-dominant in this family.
一个家族的三名成员被描述为患有先天性无痛症(IA):一名14个月大的女孩,以及她父系的父亲和祖父。所有患者自出生起就表现出对疼痛普遍漠不关心以及内脏无痛,而其他感觉完好无损。所有患者的深反射、智力发育、染色体核型、运动和感觉神经兴奋传导速度、体感诱发电位均正常。值得注意的是,在这个家族中发现IA的遗传方式为常染色体显性遗传。