Transplantation Surgery, Nagoya University, Nagoya, Japan.
Am J Transplant. 2014 Jun;14(6):1453-8. doi: 10.1111/ajt.12692. Epub 2014 Apr 11.
Living donor liver transplantation (LDLT) using a right liver graft with additional vein reconstructions has not been previously reported in a situs inversus (SI) patient. A 60-year-old man with SI was referred for LDLT for end-stage cirrhosis secondary to hepatitis B. The calculated regional volumes of the individual hepatic vein territories in the right liver graft suggested that the middle hepatic vein (MHV) tributaries and the inferior right hepatic veins (IRHVs) should be reconstructed in addition to the right hepatic vein (RHV). On the back-table, the recipient's recanalized umbilical vein graft was anastomosed to the V5 opening, and the other side of vein graft was anastomosed to the RHV and V8 opening to create a large single orifice. After total hepatectomy, the right liver graft was placed in the left subphrenic space at the reversed position. The common orifice of hepatic venous drainage from RHV, V8 and V5 was anastomosed to the anatomical RHV conduit of the recipient, followed by IRHV anastomosis to the inferior vena cava. Postoperative course was almost uneventful, and no vascular complications were experienced. Even for SI patients, LDLT using a right liver graft with reconstructions of the MHV tributaries and the IRHVs is feasible.
在镜面右位心( situs inversus ,SI)患者中,尚未有报道使用带附加静脉重建的右半肝供肝进行活体肝移植( living donor liver transplantation ,LDLT )。一名 60 岁的 SI 男性患者因乙型肝炎导致的终末期肝硬化而被转诊接受 LDLT。对右半肝供肝各肝静脉区域体积的计算表明,除右肝静脉( right hepatic vein ,RHV )外,还应重建肝中静脉( middle hepatic vein ,MHV )属支和右肝静脉下支( inferior right hepatic veins ,IRHVs )。在手术台上,受体再通的脐静脉移植物与 V5 开口吻合,静脉移植物的另一侧与 RHV 和 V8 开口吻合,以形成一个大的单一开口。全肝切除后,将右半肝供肝置于反位的左膈下间隙。RHV 、 V8 和 V5 的肝静脉共同开口与受体的解剖 RHV 导管吻合,然后进行 IRHV 吻合至下腔静脉。术后过程几乎平稳,无血管并发症发生。即使对于 SI 患者,使用带 MHV 属支和 IRHVs 重建的右半肝供肝进行 LDLT 也是可行的。